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Prof. Dr. Marc-Thorsten Hütt

Professor of Computational Systems Biology
School of Science
Constructor University Bremen gGmbH / Campus Ring 6 / 28759 Bremen / Germany
Phone number
+49 421 200-3238
Fax number
+49 421 200-3249
Email Address
mhuett@constructor.university
Office
Research II, Room 117
Research Interests

Computational Systems Biology unites approaches from mathematics, physics and computer science, in the search for basic principles and universal laws in biology. We contextualize data from high-throughput technologies using mathematical models and computational techniques, to understand the functioning of signal transduction pathways, gene regulatory networks and genome-scale metabolic systems.

Selected Publications

Spatiotemporal variation of metabolism in a plant circadian rhythm: the biological clock as an assembly of coupled individual oscillators

U Rascher, MT Hütt, K Siebke, B Osmond, F Beck, U Lüttge

Proceedings of the National Academy of Sciences 98 (20), 11801-11805

Organization of excitable dynamics in hierarchical biological networks

M Müller-Linow, CC Hilgetag, MT Hütt

PLoS computational biology 4 (9), e1000190

Connectivity and complex systems: learning from a multi-disciplinary perspective

L Turnbull, MT Hütt, AA Ioannides, S Kininmonth, R Poeppl, K Tockner, ...

Applied Network Science 3, 1-49

Dissecting the logical types of network control in gene expression profiles

C Marr, M Geertz, MT Hütt, G Muskhelishvili

BMC systems biology 2, 1-9

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease

R Häsler, R Sheibani-Tezerji, A Sinha, M Barann, A Rehman, D Esser, ...

Gut 66 (12), 2087-2097

Psychotherapy is chaotic—(not only) in a computational world

GK Schiepek, K Viol, W Aichhorn, MT Hütt, K Sungler, D Pincus, ...

Frontiers in Psychology 8, 379

Analog regulation of metabolic demand

N Sonnenschein, M Geertz, G Muskhelishvili, MT Hütt

BMC systems biology 5, 1-13

A review of planning and scheduling methods for hot rolling mills in steel production

A Özgür, Y Uygun, MT Hütt

Computers & Industrial Engineering 151, 106606

Drawing a map of invasion biology based on a network of hypotheses

M Enders, MT Hütt, JM Jeschke

Ecosphere 9 (3), e02146

The interdependent network of gene regulation and metabolism is robust where it needs to be

DF Klosik, A Grimbs, S Bornholdt, MT Hütt

Nature communications 8 (1), 534

Topology regulates pattern formation capacity of binary cellular automata on graphs

C Marr, MT Hütt

Physica A: Statistical Mechanics and its Applications 354, 641-662

Outer-totalistic cellular automata on graphs

C Marr, MT Hütt

Physics Letters A 373 (5), 546-549

Consistency analysis of metabolic correlation networks

M Müller-Linow, W Weckwerth, MT Hütt

BMC Systems Biology 1, 1-12

Hierarchical modular brain connectivity is a stretch for criticality

CC Hilgetag, MT Hütt

Trends in cognitive sciences 18 (3), 114-115

A closer look at the apparent correlation of structural and functional connectivity in excitable neural networks

A Messé, MT Hütt, P König, CC Hilgetag

Scientific reports 5 (1), 7870

Motifs in co-authorship networks and their relation to the impact of scientific publications

L Krumov, C Fretter, M Müller-Hannemann, K Weihe, MT Hütt

The European Physical Journal B 84, 535-540

Perspective: network-guided pattern formation of neural dynamics

MT Hütt, M Kaiser, CC Hilgetag

Philosophical Transactions of the Royal Society B: Biological Sciences 369 …

Datenanalyse in der Biologie: Eine Einführung in Methoden der nichtlinearen Dynamik, fraktalen Geometrie und Informationstheorie

MT Hütt

Springer-Verlag

Ca2+ dynamics during membrane excitation of green alga Chara: model simulations and experimental data

M Wacke, G Thiel, MT Hütt

The Journal of membrane biology 191, 179-192

Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome

JC Claussen, J Skiecevičienė, J Wang, P Rausch, TH Karlsen, W Lieb, ...

PLoS computational biology 13 (6), e1005361

 

Publications on Scopus
Uygun, Y. Özgür, A. Hütt, M.-T.
Engineering Materials 2024 Part F3148 pp. v-vi
Merten, D.C. Hütt, M.-T. Uygun, Y. Özgür, A. Klein, C.A.
Engineering Materials 2024 Part F3148 pp. 125-141
Merten, D. Hütt, M.-T. Uygun, Y. Özgür, A. Klein, C.-A.
Engineering Materials 2024 Part F3148 pp. 167-187
Uygun, Y. Hütt, M.-T. Özgür, A. Gulyassy, F. Niyayesh, M.
Engineering Materials 2024 Part F3148 pp. 1-13
Mendler, I.-H. Drossel, B. Hütt, M.-T.
Physica A: Statistical Mechanics and its Applications 2024 639
Zimmermann, H.H. Stoof-Leichsenring, K.R. Dinkel, V. Harms, L. Schulte, L. Hütt, M.-T. Nürnberg, D. Tiedemann, R. Herzschuh, U.
Nature Communications 2023 14 (1)
Falk, J. Eichler, E. Windt, K. Hütt, M.-T.
Advances in Complex Systems 2023 26 (7-8)
Kosmidis, K. Hütt, M.-T.
Physica A: Statistical Mechanics and its Applications 2023 626
Voutsa, V. Papadopoulos, M. Papadopoulou Lesta, V. Hütt, M.-T.
Chaos 2023 33 (8)
Rumiantsau, D. Lesne, A. Hütt, M.-T.
Physical Review E 2023 108 (1)
Lyutov, A. Uygun, Y. Hütt, M.-T.
Applied Network Science 2022 7 (1)
Jablonski, K.P. Carron, L. Mozziconacci, J. Forné, T. Hütt, M.-T. Lesne, A.
Human Genomics 2022 16 (1)
Kumar, S. D’Souza, R.N. Corno, M. Ullrich, M.S. Kuhnert, N. Hütt, M.-T.
npj Science of Food 2022 6 (1)
Falk, J. Eichler, E. Windt, K. Hütt, M.-T.
Scientific Reports 2022 12 (1)
Moreno-Zambrano, M. Ullrich, M.S. Hütt, M.-T.
Royal Society Open Science 2022 9 (2)
Schmitt, O. Nitzsche, C. Eipert, P. Prathapan, V. Hütt, M.-T. Hilgetag, C.C.
PLoS Computational Biology 2022 18 (10)
Haj Ali, S. Hütt, M.-T.
Physical Review E 2022 105 (6)
Christopher Merten, D. Hütt, M.-T. Uygun, Y.
Computers and Industrial Engineering 2022 168
Merten, D.C. Hütt, M.-T. Uygun, Y.
Journal of Iron and Steel Research International 2022 29 (1) pp. 71-79
Hütt, M.-T. Armbruster, D. Lesne, A.
Physical Review E 2022 105 (1)
Perrin-Cocon, L. Hütt, M.-T. Amoedo, N. Rossignol, R. Filipp, F.V. Lotteau, V. Diaz, O. Vidalain, P.-O. Jacquemin, C. Aublin-Gex, A. Olmstead, K. Panthu, B. Rautureau, G.J.P. André, P. Nyczka, P.
Communications Biology 2021 4 (1)
Falk, J. Eichler, E. Windt, K. Hütt, M.-T.
Foundations of Science 2021
Cakir, E. Lesne, A. Hütt, M.-T.
npj Systems Biology and Applications 2021 7 (1)
Voutsa, V. Hein, T. Kerschner, C. Kimmich, C. Lima, V. Messé, A. Parsons, A.J. Perez, J. Pöppl, R. Prell, C. Recinos, S. Battaglia, D. Shi, Y. Tiwari, S. Turnbull, L. Wainwright, J. Waxenecker, H. Hütt, M.-T. Bracken, L.J. Brovelli, A. Costescu, J. Díaz Muñoz, M. Fath, B.D. Funk, A. Guirro, M.
Journal of the Royal Society Interface 2021 18 (183)
Nyczka, P. Hütt, M.-T. Lesne, A.
Physica A: Statistical Mechanics and its Applications 2021 566
Kumar, S. D'Souza, R.N. Behrends, B. Corno, M. Ullrich, M.S. Kuhnert, N. Hütt, M.-T.
Food Research International 2021 140
Özgür, A. Uygun, Y. Hütt, M.-T.
Computers and Industrial Engineering 2021 151
Kosmidis, K. Jablonski, K.P. Muskhelishvili, G. Hütt, M.-T.
npj Systems Biology and Applications 2020 6 (1)
Hütt, M.-T. Lesne, A.
Operator Theory: Advances and Applications 2020 281 pp. 179-198
Viol, K. Said-Yürekli, S. Kronbichler, L. Kravanja-Spannberger, B. Stöger-Schmidinger, B. Hütt, M.-T. Aichhorn, W. Aas, B. Schiepek, G. Kronbichler, M. Hartl, A. Grafetstätter, C. Strasser, P. Kastinger, A. Schöller, H. Reiter, E.-M.
BMC Psychiatry 2020 20 (1)
Bendul, J. Vican, V. Hütt, M.-T.
Studies in Computational Intelligence 2020 853 pp. 232-243
Moretti, P. Hutt, M.-T.
Proceedings of the National Academy of Sciences of the United States of America 2020 117 (31) pp. 18332-18340
Hütt, M.-T. Lesne, A.
Systems Medicine: Integrative, Qualitative and Computational Approaches: Volume 1-3 2020 1-3 pp. 77-85
Ngo, Q.Q. Hütt, M.-T. Linsen, L.
Vision, Modeling and Visualization, VMV 2019 2019
Schlicht, K. Zhao, W. Gieger, C. Peters, A. Prokisch, H. Strauch, K. Baurecht, H. Weidinger, S. Rosenstiel, P. Hütt, M.-T. Knecht, C. Nyczka, P. Szymczak, S. Krawczak, M. Caliebe, A. Freitag-Wolf, S. Claringbould, A. Franke, L. Võsa, U. Kardia, S.L.R. Smith, J.A.
Human Genetics 2019
Lyutov, A. Uygun, Y. Hütt, M.-T.
Computers in Industry 2019 109 pp. 215-225
Grimbs, A. Klosik, D.F. Bornholdt, S. Hütt, M.-T.
PLoS Computational Biology 2019 15 (5)
Kosmidis, K. Hütt, M.-T.
European Physical Journal E 2019 42 (3)
Schubert, C. Hütt, M.-T.
European Labour Law Journal 2019 10 (1) pp. 3-16
Damicelli, F. Hilgetag, C.C. Hütt, M.-T. Messé, A.
Network Neuroscience 2019 3 (2) pp. 589-605
Schöller, H. Viol, K. Goditsch, H. Aichhorn, W. Hütt, M.-T. Schiepek, G.
Nonlinear Dynamics, Psychology, and Life Sciences 2019 23 (1) pp. 79-112
Hütt, M.-T.
Emergence and Modularity in Life Sciences 2019 pp. 37-49
Turnbull, L. Masselink, R. Parsons, A.J. Hütt, M.-T. Ioannides, A.A. Kininmonth, S. Poeppl, R. Tockner, K. Bracken, L.J. Keesstra, S. Liu, L.
Applied Network Science 2018 3 (1)
Blunck, H. Armbruster, D. Bendul, J. Hütt, M.-T.
Applied Network Science 2018 3 (1)
Schöller, H. Viol, K. Aichhorn, W. Hütt, M.-T. Schiepek, G.
Cognitive Neurodynamics 2018 12 (5) pp. 441-459
Moreno-Zambrano, M. Grimbs, S. Ullrich, M.S. Hütt, M.-T.
Royal Society Open Science 2018 5 (10)
Chankov, S. Hütt, M.-T. Bendul, J.
International Journal of Production Research 2018 56 (14) pp. 4781-4801
Messé, A. Hütt, M.-T. Hilgetag, C.C.
PLoS Computational Biology 2018 14 (4)
Enders, M. Hutt, M.-T. Jeschke, J.M.
Ecosphere 2018 9 (3)
Chankov, S. Hütt, M.-T. Bendul, J.
Journal of Manufacturing Systems 2018 46 pp. 127-136
Häsler, R. Nikolaus, S. Schäuble, S. Kaleta, C. Franke, A. Fretter, C. Müller, W. Hütt, M.-T. Krawczak, M. Schreiber, S. Rosenstiel, P. Sheibani-Tezerji, R. Sinha, A. Barann, M. Rehman, A. Esser, D. Aden, K. Knecht, C. Brandt, B.
Gut 2017 66 (12) pp. 2087-2097
Klosik, D.F. Grimbs, A. Bornholdt, S. Hütt, M.-T.
Nature Communications 2017 8 (1)
Claussen, J.C. Skiecevičienė, J. Wang, J. Rausch, P. Karlsen, T.H. Lieb, W. Baines, J.F. Franke, A. Hütt, M.-T.
PLoS Computational Biology 2017 13 (6)
Grimbs, A. Kuhnert, N. Ullrich, M.S. Shrestha, A. Rezk, A.S.D. Grimbs, S. Hakeem Said, I. Schepker, H. Hütt, M.-T. Albach, D.C. Brix, K.
Frontiers in Plant Science 2017 8
Schiepek, G.K. Viol, K. Aichhorn, W. Hütt, M.-T. Sungler, K. Pincus, D. Schöller, H.J.
Frontiers in Psychology 2017 8 (APR)
Damicelli, F. Hilgetag, C.C. Hütt, M.-T. Messé, A.
Chaos 2017 27 (4)
Fretter, C. Lesne, A. Hilgetag, C.C. Hütt, M.-T.
Scientific Reports 2017 7
Beber, M.E. Muskhelishvili, G. Hütt, M.-T.
Database 2016 2016
Chankov, S. Hütt, M.-T. Bendul, J.
International Journal of Production Research 2016 54 (20) pp. 6033-6051
Knecht, C. Fretter, C. Rosenstiel, P. Krawczak, M. Hütt, M.-T.
Scientific Reports 2016 6
Meyer, M. Hütt, M.-T. Bendul, J.
International Journal of Production Research 2016 54 (14) pp. 4145-4160
Ngo, Q.Q. Hütt, M.-T. Linsen, L.
Computer Graphics Forum 2016 35 (3) pp. 301-310
Messé, A. Hütt, M.-T. König, P. Hilgetag, C.C.
Scientific Reports 2015 5
Kosmidis, K. Beber, M. Hütt, M.-T.
Advances in Complex Systems 2015 18 (1-2)
Hao, Y. Armbruster, D. Hütt, M.-T.
PLoS ONE 2015 10 (5)
Hütt, M.-T. Lüttge, U. Thellier, M.
Rhythms in Plants: Dynamic Responses in a Dynamic Environment 2015 pp. 279-321
Hütt, M.-T.
British Journal of Clinical Pharmacology 2014 77 (4) pp. 597-605
Möller, S. Hameister, H. Hütt, M.-T.
Physica A: Statistical Mechanics and its Applications 2014 414 pp. 216-226
Garcia, G.C. Lesne, A. Hilgetag, C.C. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2014 90 (5)
Hütt, M.-T. Kaiser, M. Hilgetag, C.C.
Philosophical Transactions of the Royal Society B: Biological Sciences 2014 369 (1653)
Klosik, D.F. Bornholdt, S. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2014 90 (3)
Hilgetag, C.C. Hütt, M.-T.
Trends in Cognitive Sciences 2014 18 (3) pp. 114-115
Grace, M. Hütt, M.-T.
European Physical Journal B 2014 87 (2)
Becker, T. Meyer, M. Beber, M.E. Windt, K. Hütt, M.-T.
Lecture Notes in Logistics 2013 pp. 141-150
Beber, M.E. Hütt, M.-T.
Lecture Notes in Production Engineering 2013 Part F1157 pp. 3-16
Beber, M.E. Armbruster, D. Hütt, M.-T.
European Physical Journal B 2013 86 (11)
Grace, M. Hütt, M.-T.
Journal of the Royal Society Interface 2013 10 (81)
Beber, M.E. Fretter, C. Jain, S. Sonnenschein, N. Müller-Hannemann, M. Hütt, M.-T.
Journal of the Royal Society Interface 2012 9 (77) pp. 3426-3435
Becker, T. Beber, M.E. Windt, K. Hütt, M.-T.
CIRP Journal of Manufacturing Science and Technology 2012 5 (4) pp. 309-318
Hütt, M.-T. Jain, M.K. Hilgetag, C.C. Lesne, A.
Chaos, Solitons and Fractals 2012 45 (5) pp. 611-618
Beber, M.E. Hütt, M.-T.
Logistics Research 2012 5 (3-4) pp. 79-87
Sonnenschein, N. Marr, C. Hütt, M.-T.
Metabolites 2012 2 (3) pp. 632-647
Garcia, G.C. Lesne, A. Hütt, M.-T. Hilgetag, C.C.
Frontiers in Computational Neuroscience 2012
Fretter, C. Müller-Hannemann, M. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2012 85 (5)
Sonnenschein, N. Golib Dzib, J.F. Lesne, A. Eilebrecht, S. Boulkroun, S. Zennaro, M.-C. Benecke, A. Hütt, M.-T.
BMC Systems Biology 2012 6
Yordanov, P. Tyanova, S. Hütt, M.-T. Lesne, A.
International Journal of Bifurcation and Chaos 2011 21 (7) pp. 1895-1905
Windt, K. Hütt, M.-T.
CIRP Annals - Manufacturing Technology 2011 60 (1) pp. 473-476
Becker, T. Beber, M.E. Windt, K. Hütt, M.-T. Helbing, D.
Journal of Statistical Mechanics: Theory and Experiment 2011 2011 (5)
Sonnenschein, N. Geertz, M. Muskhelishvili, G. Hütt, M.-T.
BMC Systems Biology 2011 5
Hameister, J. Helm, W.E. Hütt, M.-T. Dehnert, M.
Studies in Classification, Data Analysis, and Knowledge Organization 2010 pp. 627-637
Marr, C. Theis, F.J. Liebovitch, L.S. Hütt, M.-T.
PLoS Computational Biology 2010 6 (7) pp. 31-
Smith, J. Hütt, M.-T.
Systems Biology in Psychiatric Research: From High-Throughput Data to Mathematical Modeling 2010 pp. 243-276
Kuhn, A. Dehnert, M. Helm, W.E. Hütt, M.-T.
BioSystems 2010 100 (3) pp. 215-224
Geberth, D. Hütt, M.-T.
Physica A: Statistical Mechanics and its Applications 2010 389 (2) pp. 249-258
Sonnenschein, N. Hütt, M.-T. Stoyan, H. Stoyan, D.
BMC Systems Biology 2009 3
Liebovitch, L.S. Shehadeh, L.A. Jirsa, V.K. Hütt, M.-T. Marr, C.
Handbook of Research on Computational Methodologies in Gene Regulatory Networks 2009 pp. 405-428
Hadzhiev, B. Windt, K. Bergholz, W. Hütt, M.-T.
Advances in Complex Systems 2009 12 (6) pp. 549-564
Hütt, M.-T. Lesne, A.
Frontiers in Neuroinformatics 2009 3 (SEP)
Schneeweiss, C. Garstka, M. Smith, J. Hütt, M.-T. Springer, S.
Molecular Immunology 2009 46 (10) pp. 2054-2063
Marr, C. Hütt, M.-T.
Physics Letters, Section A: General, Atomic and Solid State Physics 2009 373 (5) pp. 546-549
Müller-Linow, M. Hilgetag, C.C. Hütt, M.-T.
PLoS Computational Biology 2008 4 (9)
Geberth, D. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2008 78 (3)
Marr, C. Geertz, M. Hütt, M.-T. Muskhelishvili, G.
BMC Systems Biology 2008 2
Marr, C. Hütt, M.-T. Müller-Linow, M.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2008 77 (2)
Hütt, M.-T. Lüttge, U.
Rhythms in Plants: Phenomenology, Mechanisms, and Adaptive Significance 2007 pp. 313-339
Müller-Linow, M. Weckwerth, W. Hütt, M.-T.
BMC Systems Biology 2007 1
Hilgardt, C. Müller, S.C. Hütt, M.
Nonlinear Biomedical Physics 2007 1
Marr, C. Müller-Linow, M. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2007 75 (4)
Müller-Linow, M. Marr, C. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2006 74 (1)
Dehnert, M. Helm, W.E. Hütt, M.-T.
Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2006 74 (2)