MoLife Research Seminar: Ms. Tian Ma
Talk by:
Ms. Tian Ma, PhD student of group U. Kortz, Professor of Chemistry, Jacobs University Bremen, Germany
Title:
'Organically-Derivatized Polyoxometalates: Tuning of Bioactivity by Ligand Functionalization'
Abstract:
Polyoxometalates (POMs) are discrete polynuclear metal oxides with a large structural and compositional variety, and a multitude of properties resulting in applications in fundamental and applied science.1
In recent years our group has developed the class of organoantimony(III)-containing POMs and we have demonstrated bioactivity with a focus on bacterial inhibition. Most importantly, it was shown that the number and type of grafted organoantimony(III) groups have a strong influence on the resulting bioactivity of the polyanion.2
Here we show recent developments in this area of research.
1 (a) M. T. Pope, Heteropoly and Isopoly Oxometalates, Springer, Berlin, 1983. (b) M. T. Pope, A. Müller, Polyoxometalates: from Platonic Solids to Antiviral Activity; Kluwer Academic Publishers: Dordrecht, The Netherlands, 1994.
2 (a) P. Yang, Z. Lin, B. S. Bassil, G. Alfaro-Espinoza, M. S. Ullrich, M. X. Li, C. Silvestru, U. Kortz, Inorg. Chem. 2016, 55, 3718–3720. (b) P. Yang, Z. Lin, G. Alfaro-Espinoza, M. S. Ullrich, C. I. Rat, C. Silvestru, U. Kortz, Inorg. Chem. 2016, 55, 251–258. (c) P. Yang, B. S. Bassil, Z. Lin, A. Haider, G. Alfaro-Espinoza, M. S. Ullrich, C. Silvestru, U. Kortz, Chem. Eur. J. 2015, 21, 15600–15606. (d) M. Barsukova-Stuckart, L. F. Piedra-Garza, B. Gautam, G. Alfaro-Espinoza, N. V. Izarova, A. Banerjee, B. S. Bassil, M. S. Ullrich, H. J. Breunig, C. Silvestru, U. Kortz, Inorg. Chem. 2012, 51, 12015–12022. (e) L. F. Piedra-Garza, M. H. Dickman, O. Moldovan, H. J. Breunig, U. Kortz, Inorg. Chem. 2009, 48, 411–413.
ALL ARE WELCOME!
Further information by:
Prof. Dr. Ulrich Kortz, Professor of Chemistry - Email: u.kortz@jacobs-university.de - Tel: +49 421 200-3235 - Homepage: http://ukortz.user.jacobs-university.de