Prof. Jürgen Fritz

Biophysics and Didactics of Physics
School of Science
Campus Ring 1 28759 Bremen Germany
Phone number
+49 421 200-3522
Fax number
+49 421 200-3229
Email Address
Research III, Room 56
Research Interests

Current research interests include molecular biophysics, atomic force microscopy on biomolecules, force spectroscopy and nanomechanics, single molecule methods, label-free biosensing, surface functionalization, microfluidics and microcontact printing, nanotechnology.

Our group investigates the structure and interaction of single biomolecules by atomic force microscopy (AFM), and we work on detecting the presence and activity of biomolecules with nanomechanical biosensors. Both approaches aim for a better understanding of biomolecular systems on a fundamental level, in order to develop new bioanalytical tools and explore the application of biomolecules in nanotechnology.

University Education
1988 - 1991
University of Karlsruhe (Germany), Vordiplom
1991 - 1994
University of Heidelberg (Germany), Physikdiplom
1995 - 1998
University of Basel (Switzerland), Institute of Physics
PhD student at Novartis
Dissertation in experimental physics


Research and Teaching Positions
1998 - 2000
IBM Zurich Research Laboratory (Rüschlikon, Switzerland), Postdoc
2000 - 2003
Massachusetts Institute of Technology (Cambridge, USA), Media Laboratory, Postdoc and staff research scientist
Since May 2003
Assistant Professor of Biophysics at Jacobs University Bremen (former International University Bremen), Germany
Selected Publications


  • J. Fritz, A. G. Katopodis, F. Kolbinger, D. Anselmetti: Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy, Proc. Natl. Acad. Sci. USA 95 (1998) 12283-12288.
  • J. Fritz, M. K. Baller, H. P. Lang, H. Rothuizen, P. Vettiger, E. Meyer, H.-J. Güntherodt, Ch. Gerber, J. K. Gimzewski: Translating biomolecular recognition into nanomechanics, Science 288 (2000) 316-318.
  • J. Fritz, E. B. Cooper, S. Gaudet, P. K. Sorger, S. R. Manalis: Electronic detection of DNA by its intrinsic molecular charge, Proc. Natl. Acad. Sci. USA 99 (2002) 14142-14146
  • I. Pera and J. Fritz: Sensing lipid bilayer formation and expansion with a microfabricated cantilever array, Langmuir 23 (2007) 1543-1547.
  • J. Fritz: Cantilever Biosensors, Analyst 133 (2008) 855-863.
  • S. Maurer, J. Fritz, G. Muskhelishvili: A systematic in vitro study of nucleoprotein complexes formed by bacterial nucleoid-associated proteins revealing novel types of DNA organization, J. Mol. Biol. 387 (2009) 1261-1276.