Prof. Werner Nau

Supramolecular Chemistry and Chemical Biology
School of Science
Campus Ring 1 | 28759 Bremen | Germany
Phone number
Res. III: +49 421 200-3233 | RLH: - 4339
Fax number
+49 421 200 3102
Email Address
Reimar Lüst Hall, Room : 245 | Res. III, Room: 112
Research Interests

We are an international research group whose scientific concern lies at the interphase between physical-organic chemistry and supramolecular chemistry focused on the management of supramolecular assemblies for several applications in sensing, catalysis, pharmaceutical industry, biological systems… One component of our work involves synthesis and characterization of organic chromo-fluorophores, with synthetic and spectroscopic experience from conventional techniques, such UV-vis/ Fluorescence and NMR spectrometry to fast-time resolved techniques as time-correlated Single-Photon counting. The main focus of the research lies in the area of supramolecular chemistry to better understand the nature of the molecular interactions, directing the challenging use of water as solvent. We study the interaction of different macrocyclic hosts (mostly CDs, CBs, and CXs) with a variety of guests, by using spectroscopic (Uv-vis, fluorescence, and NMR) and calorimetric techniques (ITC and DSC). The resulting host-guest supramolecular complexes can be used in analytical applications as well as in drug delivery.  The macrocyclic host has been also applied as catalyst for chemical reactions inside its cavity. We have been also concerned in the development of kinetic models, including the analysis of the kinetic data by advanced computer-based approaches like the development of fitting and numerical integration routines. Recently we merged the areas of supramolecular and biological chemistry to monitor the actual transport of molecules through the hydrophobic membrane barrier, by encapsulating supramolecular host-dye complexes in artificial vesicles (LUVs and GUVs). We investigate the use superchaotropic anions to carry hydrophilic compounds through artificial and cellular membranes. For the analysis, we employ different fluorescence methods such as time-resolved fluorescence, confocal microscopy, and flow cytometry.


Prof. Dr. Werner M. Nau

Group Members:
Dipl.-Chem. Thomas Schwarzlose, Lecturer, Germany
Dr. Sabrina Döpke-Renken, Technical Assistant, Germany
Dr. Andrea Barba-Bon, Research Associate, Spain
Dr. Ivana Nikšic-Franjic, Postdoc, Croatia 
Dr.Ruixue Jiang, Postdoc, China
Meghna Keerampally, PhD Student, India
Maryam Ashjari, PhD Student, Iran
Osama Abuhasan, PhD Student, Jordan  
Zhaofei Zhang, Master Student, China
Immacolata De Luca, Visiting Student, Italy

Former PhD Students:

Dr. Yao Chen, China (2022)

Dr. Mohammad Al-Najjar, Jordan (2021)

Dr. Francisco Javier Rodríguez Mejías, Spain (2021)

Dr. Yan-Cen Liu, China (2020)

Dr. Mohamed Nilam, Sri Lanka (2020)

Dr. Shuai Zhang, China (2019)

Dr. Alexandra Irina Lazar, Romania (2018)

Dr. Khaleel Assaf, Jordan (2015)

Dr. Amir Norouzy, Iran (2014)

Dr. Garima Ghale, Nepal (2014)

Dr. Indrajit Ghosh, India (2013)

Dr. Vanya Uzunova, Bulgaria (2011)

Dr. Mara Florea, Romania (2011)

Dr. Roy D'Souza, India/Portugal (2011)

Dr. Roland Meyer, Germany (2011)

Dr. Hamdy Saad El-Sheshtawy, Egypt (2011)

Dr. Apurba L. Koner, India (2009)

Dr. Andreas Hennig, Germany (2007)

Dr. Harekrushna Sahoo, India (2007)

Dr. Huseyin Bakirci, France (2005)

Dr. Gabriele Gramlich, Germany (2004)

Prof. Dr. Fang Huang, China (2004)

Dr. Xiaojuan (Amy) Wang, China (2004)

Dr. Cesar Marquez, Spain (2003)

Prof. Dr. Uwe Pischel, Germany (2001)

Dr. Xiangyang Zhang, China (2001)


Former Postdocts:

Dr Suhang He, China (2002) 

Dr. Maik Jacob, Germany (2021)

Dr. Frank Biedermann, Germany (2013)

Dr. Ana Rei, Portugal (2011)

Dr. David Bailey, Canada (2008)

Dr. Jyotirmayee Mohanty, India (2005)

Prof. Dr. Patra Digambara, India (2002)

Are you interested in joining us? 

We are always looking for highly motivated students as well as Postdoctoral researchers, who share our interest in supramolecular chemistry, photophysics, and chemical biology.  Do not hesitate and  let us know about your motivation, send an email to 

We are an international team where English is the language of the group. German is not required.

Selected Publications

* ORCID: 0000-0002-7654-6232

314A)   Pramod, M.; Alnajjar, M.A.; Schöpper, S.N.; Schwarzlose,T.; Nau, W.M.; Hennig,A. Adamantylglycine as a high-affinity peptide label for membrane transport monitoring and regulation. Chem. Commun. 2024. DOI: 10.1039/d4cc00602j. 

313A)   Jiang,R.; Nilam, M.; Hennig, A.;   Nau, W. M. Dual-Color Real-Time Chemosensing of A Compartmentalized Reaction Network Involving Enzyme-Induced Membrane Permeation of Peptides. Adv. Mater. 2024. 36,2306922. 

312A)  Barba-Bon, A; Gumerova, N. I.; Tanuhadi, E.; Ashjari, M.; Chen,Y.;  Rompel, A.; Nau, W.M.; All-inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers. Adv. Mater. 2024,36,2309219.

311R)  Assaf, K. I.; Nau, W. M. Dispersion Interactions in Condensed Phases and inside Molecular Containers. Acc. Chem. Res. 2023. 56, 23, 3451–3461.

310A) McGuire, K.; He,S.; Gracie, J.; Bryson, C.; Zheng, D.; Clark, A. W.; Koehnke, J.;   France, D.J.; Nau, W. M.; Lee, T.-C.; Peveler, W. J. Supramolecular Click Chemistry for Surface Modification of Quantum Dots Mediated by Cucurbit[7]uril. ACS Nano 2023, 17, 21, 21585–21594.

309) He, S.; Huang, B.; Xiao, B.;  Chang, S.; Podalko, M.; Nau, W.M. Stabilization of Guest Molecules inside Cation-Lidded Cucurbiturils Reveals that Hydration of Receptor Sites Can Impede Binding. Angew. Chem. Int. Ed., 2023, e202313864. 

308) Assaf, K. I., Nau, W. M., Large Anion Binding in WaterOrg. Biomol. Chem. 2023, 21, 6636-6651.

307A) Chen, Y. Barba-Bon, A., Grüner, B., Wintherhalter, M., Aksoyoglu, M. A., Pangeni, S., Ashjari, M., Brix, K., Salluce, G., Folgar-Cameán, Y., Montenegro, J., Nau, W. M., Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides, J. Am. Chem. Soc.2023,145, 24, 13089–13098.


314A)   Pramod, M.; Alnajjar, M.A.; Schöpper, S.N.; Schwarzlose,T.; Nau, W.M.; Hennig,A. Adamantylglycine as a high-affinity peptide label for membrane transport monitoring and regulation. Chem. Commun. 2024. DOI: 10.1039/d4cc00602j. 

313A)   Jiang,R.; Nilam, M.; Hennig, A.;   Nau, W. M. Dual-Color Real-Time Chemosensing of A Compartmentalized Reaction Network Involving Enzyme-Induced Membrane Permeation of Peptides. Adv. Mater. 2024. 36,2306922. 

312A)  Barba-Bon, A; Gumerova, N. I.; Tanuhadi, E.; Ashjari, M.; Chen,Y.;  Rompel, A.; Nau, W.M.; All-inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers. Adv. Mater. 2024,36,2309219.


311R)  Assaf, K. I.; Nau, W. M. Dispersion Interactions in Condensed Phases and inside Molecular Containers. Acc. Chem. Res. 2023. 56, 23, 3451–3461.

310A) McGuire, K.; He,S.; Gracie, J.; Bryson, C.; Zheng, D.; Clark, A. W.; Koehnke, J.;   France, D.J.; Nau, W. M.; Lee, T.-C.; Peveler, W. J. Supramolecular Click Chemistry for Surface Modification of Quantum Dots Mediated by Cucurbit[7]uril. ACS Nano 2023, 17, 21, 21585–21594.

309) He, S.; Huang, B.; Xiao, B.;  Chang, S.; Podalko, M.; Nau, W.M. Stabilization of Guest Molecules inside Cation-Lidded Cucurbiturils Reveals that Hydration of Receptor Sites Can Impede Binding. Angew. Chem. Int. Ed., 2023, e202313864. 

308) Assaf, K. I., Nau, W. M., Large Anion Binding in WaterOrg. Biomol. Chem. 2023, 21, 6636-6651.

307A) Chen, Y. Barba-Bon, A., Grüner, B., Wintherhalter, M., Aksoyoglu, M. A., Pangeni, S., Ashjari, M., Brix, K., Salluce, G., Folgar-Cameán, Y., Montenegro, J., Nau, W. M., Metallacarborane Cluster Anions of the Cobalt Bisdicarbollide-Type as Chaotropic Carriers for Transmembrane and Intracellular Delivery of Cationic Peptides, J. Am. Chem. Soc.2023,145, 24, 13089–13098.

306A) Paatelaien, M., Lahikainen, M., Berdin, A., Kuntze, K., Nau, W. M., Nonappa A. P. Hydrogel Lasers Via Supramolecular Host-Guest Complexation. Adv. Optical Mater. 2023, 2300232.

305A) S. Moorthy, H. Lambert, N. Mohan, T. Schawrzlose, W.M.Nau, E. Kalenius, T-C. Lee, Noncovalent Modulation of Chemoselectivity in the Gas Phase Leads to a Switchover in Reaction Type from Heterolytic to Homolytic to Electrocyclic Cleavage. Angew. Chem. Int.Ed2023, e202303491.

304A) M. H. Jacob, R. N. D´Souza, A. I. Lazar. W. M. Nau,Diffusion-Enhanced Förste Resonance Energy Transfer in Flexible Peptides: From the Haas-Steinberg Partial Differential Equation to a Closed Analytical Expression Polymers. 2023, 15, 705.

303A)  X. Hu, J. Zhao, Y. Zhao, H. Zhang, Q. Wang, B. Ge, X. Wang, H. He, W. M. Nau, X. WangF. Huang, Direct Observation and Real-Time Tracking of an Extraordinarily Stable Folding Intermediate in Mitotic Arrest Deficient Protein 2 Folding by Single-Molecule Fluorescence Resonance Energy TransferJ. Phys. Chem. Lett., 202314, 763-769.

302A)  F.J. R. Mejías, S. He, R. M. Varela, J. M. G. Molinillo, A. Barba-Bon, W. M. Nau and F. A. Macías, Stability and pKa Modulation of Aminophenoxazinones and Their Disulfide Mimics by Host–Guest Interaction with Cucurbit[7]uril. Direct Applications in Agrochemical Wheat ModelsJ. Agric. Food Chem., 202317, 480-487.


301C)  J. Zhang, D. Gabel, K. I. Assaf, W. M. Nau. A Fluorescein-Substituted Perbrominated Dodecaborate Cluster as an Anchor Dye for Large Macrocyclic Hosts and Its Application in Indicator Displacement AssaysOrg. Lett202224, 9184-9188.

300A)   A. Barba-Bon, G. Salluce, I. Lostalé-Seijo, K.I. Assaf, A. Hennig, J. Montenegro, W.M. Nau, Boron Clusters as Broadband Membrane CarriersNature2022603, 637-642.

299A)  M. Masi, J. Vergalli, I. Ghai, A. Barba-Bon, T. Schembri, W. M. Nau, D. Lafirre, M. Winterhalter, J.-M. Pagès. Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane. Commun Biol. 20225, 1059.

298C) M. Nilam, S. Karmacharya, W. M. Nau, A. Hennig, Proton-Gradient-Driven Sensitivity Enhancement of Liposome-Encapsulated Supramolecular ChemosensorsAngew. Chem. Int. Ed. 2022, e202207950.

297A) B. Xiao, S. He, M. Sun, J. Zhou, Z. Wang, Y. Li, S. Liu, W. M. Nau, S. Chang, Dynamic Interconversions of Single Molecules Probed by Recognition Tunneling at Cucurbit[7]uril-Functionalized Supramolecular JunctionsAngew. Chem. Int. Ed. 2022, e202203830.

296A) S. Bhattacharya, A. Barba-Bon, T. A. Zewdie, A. B. Müller, T. Nisar, A. Chmielnicka, I.A. Rutkowska, C. J. Schürmann, V. Wagner, N. Kuhnert, P. J. Kulesza, W. M. Nau, U. Kortz, Discrete, Cationic Palladium(II)-Oxo Clusters via f-Metal Ion Incorporation and their Macrocyclic Host-Guest Interactions with SulfonatocalixarenesAngew. Chem. Int. Ed. 2022, e202203114.

295A)    F. N. Tehrani, K. I. Assaf, R. Hein, C.M. E. Jensen, T. C. Nugent, W. M. Nau,  Supramolecular Catalysis of a Catalysis-Resistant Diels-Alder Reaction: Rapid Dimerization of Cyclopentadiene inside Cucurbit[7]uril. ACS Catal. 202212, 2261−2269.

294A)   T. Marei, M. K. Al-Joumhawy, M. A. Alnajjar, W. M. Nau,  K.I. Assaf and D. Gabel. Binding affinity of aniline-substituted dodecaborates to cyclodextrins. Chem. Commun., 202258, 2363-2366.

293A)    A. Norouzy,  A. I. Lazar,  M. H. Karimi‑Jafari, R. Firouzi, W. M. Nau. Electrostatically induced pKa shifts in oligopeptides: the upshot of neighboring side chains. Amino Acids, 202254, 277–287


292A)   M. Molkenthin, W. M. Nau,  B. J. Nachtsheim. Efficient Hydro‐ and Organogelation by Minimalistic Diketopiperazines Containing a Highly Insoluble Aggregation‐Induced, Blue‐Shifted Emission Luminophore**. Chem. Eur. J. 202127, 16488-16497.

291A)    X. Wang, X. Ma,  C. Liu, B. Ge, H. He, Q. Dai, Z. Zhang, J. Yu, W. M. Nau, F. Huang. Self-assembled Theranostic Microcarrier Targeting Tumor Cells with High Metastatic Potential. Materials & Design2021212 ,110196.

290A)   M. A. Alnajjar, W. M. Nau, A. Hennig, A reference scale of cucurbit[7]uril binding affinities.  Org. Biomol. Chem., 202119, 8521-8529.

289A)    N. Saleh, S. Al-Jassabi, A. Eid, W. M. Nau, Cucurbituril Ameliorates Liver Damage Induced by Microcystis aeruginosa in a Mouse Model, Front. Chem. 2021, doi: 10.3389/fchem.2021.660927.

288A)    S. Pangeni, J. Prajapati, B. Dahyabhai, A. Jayesh, N. Mohamed, W. M. Nau, U. Kleinekathöfer, M. Winterhalter, Large Peptide Permeation Through a Membrane Channel: Understanding Protamine Translocation Through CymA from Klebsiella Oxytoca Angew. Chem. Int. Ed. 202160, 8089-8094.

287A)    Z. Hou, W. M. Nau, R. Hoogenboom, Reversible covalent locking of a supramolecular hydrogel via UV-controlled anthracene dimerizationPolymer Chem. 202112, 307–315.

286A)    H. He, L. Liu, X. Chen, Q. Wang, X. Wang, W. M. Nau, F. Huang, Carbon Dot Blinking Enables Accurate Molecular Counting at Nanoscale ResolutionAnal. Chem. 202193, 3968–3975.

285A)    Y.-C. Pan, A. Barba-Bon, H. W. Tian, F. Ding, A. Hennig, W. M. Nau, D. S. Guo, An Amphiphilic Sulfonatocalix[5]arene as a Novel Activator for Membrane Transport of Lysine-rich Peptides and ProteinsAngew. Chem. 2021133, 1903–1910; Angew. Chem. Int. Ed. 202160, 1875–1882.

284A)   M. Nilam, S. Collin, S. Karmacharya, A. Hennig, W. M. Nau, Membrane Permeability and its Activation Energies in Dependence on Analyte, Lipid, and Phase Type Obtained by Fluorescent Artificial Receptor Membrane Assay, ACS Sensors 20216, 175–182.


283A)  S. He, A. Zhiti, A. Barba-Bon, A. Hennig, W. M. Nau, Real-Time Parallel Artificial Membrane Permeability Assay based on Supramolecular Fluorescent Artificial ReceptorsFontiers Chem. 20208, 806; doi: 10.3389/fchem.2020.00806

282A)  A. Hennig, W. M. Nau. Interaction of Cucurbit[7]uril with Protease Substrates: Application to Nanosecond Time-Resolved Fluorescence Assays. Frontiers Chem. 2020,8,806, doi:10.3389/fchem.2020.00806.

281A)  F. Biedermann, G. Ghale, A. Hennig, W. M. Nau. Fluorescent Artificial Receptor-based Membrane Assay (FARMA) for Spatiotemporally Resolved Monitoring of Biomembrane Permeability. Communic. Biol. 2020,3,383.

280A)  M. Shahabi, R. Hajihosseini, W. M. Nau, K. Akbari Noghabi, A. Norouzy. Augmenting Peptide Flexibility by Inserting Gamma-Aminobutyric Acid (GABA) in Their Sequence. Int. J. Pept. Res. Ther. 202026, 2633-2640.

279A)  M. Huang, M. Sun, X. Yu, S. He, S. Liu, W. M. Nau, Y. Li, T. Wu, Y. Wang, S. Chang, J. He. Reliably Probing the Conductance of a Molecule in a Cavity via van der Waals Contacts. J. Phys. Chem. C 2020, 29, 16143–16148.

278A)  K. I. Assaf, H. Abed Alfattah, A. F. Eftaiha, S. K. Bardaweel, M. A. Alnajjar, F. A. Alsoubani, A. K. Qaroush, M. I. El-Barghouthi, W. M. Nau. Encapsulation of Ionic Liquids inside Cucurbiturils. ChemistrySelect 202018, 2120–2128.

277A)  M. Nilam, C. Huang, S. Karmacharya, G. H. Aryal, L. Huang, W. M. Nau, K. I. Assaf. Host-Guest Complexation Affects Perylene-Based Dye Aggregation. ChemistrySelect 20205, 5850–5854.

276A)  K. I. Assaf, J. Holub, E. Bernhardt, J. M. Oliva-Enrich, M. I. Fernández Pérez, M. Canle Lopez, J. A. Santaballa, J. Fanfrlík, D. Hnyk, W. M. Nau. Face-Fusion of Icosahedral Boron Hydride Increases Affinity to γ-Cyclodextrin: closo,closo-[B21H18] as an Anion with Very Low Free Energy of Dehydration. ChemPhysChem 202021, 971–976.

275B)  A. Hennig, W. M. Nau. Cucurbituril-Based Sensors and Assays. in “Cucurbiturils and Related Macrocycles”, Ed.: K. Kim, RSC Press, Cambridge, UK, 2020, 121–149.

274B)  K. I. Assaf, W. M. Nau. Cucurbituril Properties and the Thermodynamic Basis of Host-Guest Binding. in “Cucurbiturils and Related Macrocycles”, Ed.: K. Kim, RSC Press, Cambridge, UK, 2020, 54–85.

273A)  A. Wagner, K. H. Ly, N. Heidary, I. Szabó, K. I. Assaf, S. J. Barrow, K. Sokołowski, N. Kornienko, M. F. Kuehnel, E. Rosta, I. Zebger, W. M. Nau, O. Scherman, E. Reisner. Host-guest-Chemistry Meets Electrocatalysis: Cucurbit[6]uril on a Au Surface as Hybrid System in CO2 Reduction. ACS Catalysis 202010, 751–761.


272A)  A. Barba-Bon, Y.-C. Pan, F. Biedermann, D.-S. Guo, W. M.  Nau, Werner; A. Hennig, Fluorescence Monitoring of Peptide Transport Pathways into Large and Giant Vesicles by Supramolecular Host-Dye PairsJ. Am. Chem. Soc.2019, 141, 20137–20145.

271C)  S. Zhang, L. Grimm, Z. Miskolczy, L. Biczók, F. Biedermann W. M. Nau, Binding Affinities of Cucurbit[n]urils with CationsChem. Commun.2019, 55, 14131–14134.

270C)  Y.-C. Liu, W. M. Nau, A. Hennig, A Supramolecular Five-Component Relay Switch that Exposes the Mechanistic Competition of Dissociative versus Associative Binding to Cucurbiturils by Ratiometric Fluorescence MonitoringChem. Commun.2019, 55, 14123-14126.

269C)  S. El Anwar, K. I. Assaf, B. Begaj, M. A. Samsonov, Z. Růžičková, J. Holub, D. Bavol, Werner M. Nau, D. Gabel, B. Grüner, Versatile, one-pot introduction of nonahalogenated 2-ammoniodecaborate ions as boron cluster scaffolds into organic molecules; host-guest complexation with g-cyclodextrinChem. Commun.2019, 55, 13669–13672.

268A)  S. J. Barrow, K. I. Assaf, A. Palma, W. M. Nau, O. A. Scherman, Preferential Binding of Unsaturated Hydrocarbons in Aryl–Bisimidazolium•Cucurbit[8]uril Complexes Furbishes Evidence for Small-Molecule π–π InteractionsChem Sci.2019, 10, 10240–10246.

267A)  Y.-C. Liu, S. Peng, L. Angelova, W. M. Nau, A. Hennig, Label-Free Fluorescent Kinase and Phosphatase Enzyme Assays with Supramolecular Host-Dye PairsChemistryOpen2019, 8, 1350–1354.

266A)  D. Maity, K. I. Assaf, C. Hirschhäuser, W. Sicking, W. M. Nau, C Schmuck, A Selective Cucurbit[8]uril-Peptide Beacon Ensemble for Ratiometric Fluorescence Detection of PeptidesChem. Eur. J.2019, 25, 13088–13093.

265R)  K. I. Assaf, D. Das, W. M. Nau, Applications of Cucurbiturils in Medicinal Chemistry and Chemical BiologyFrontiers Chem.2019, 7, 619.

264A)  Y. Wang, X. Wang, X. Ma, Q. Chen, H. He, W. M. Nau, F. Huang, Co-Assembly of Gold Nanoclusters with Nucleic Acids: Sensing, Bioimaging and Gene TransfectionPart. Part. Syst. Charact.2019, 36, 1900281.

263A)    K. I. Assaf, B. Begaj, A. Frank, M. Nilam, A. Mougharbel, U. Kortz, J. Nekvinda, B. Gruner, D. Gabel, W. M. Nau, “High-affinity Binding of Metallacarborane Cobalt Bis(dicarbollide) Anions to Cyclodextrins and Application to Membrane Translocation”J. Org. Chem. 201984, 11790–11798.

262A)  W. K. Chio, W. J. Peveler, K. I. Assaf, S. Moorthy, W. M. Nau, I. P. Parkin, M. Olivo, T.-C. Lee, Selective Detection of Nitroexplosives Using Molecular Recognition within Self-Assembled Plasmonic NanojunctionsJ. Phys. Chem. C2019, 123, 15769–15776.

261A)  A. Farcas, K. I. Assaf, A.-M. Resmerita, L. Sacarescu, M. Asandulesa, P.-H. Aubert, Werner M. Nau, Cucurbit[7]uril-Threaded Poly(3,4-ethylenedioxythiophene): A Novel Processable Conjugated PolyrotaxaneEur. J. Org. Chem.2019, 21, 3442-3450.

260A)  E.-L. Ursu, M. Balan, W. M. Nau, M. Nilam, Y.-C. Liu, A. Farcas, A. Hennig. Synthesis and Photophysical Properties of Inclusion Complexes Between Conjugated Polyazomethines with g-Cyclodextrin and its Tris-O Methylated Derivative. Eur. Polym. J2019, 113, 236–243.

259C)  S. Zhang, K. I. Assaf, C. Huang, A. Hennig, W. M. Nau. Ratiometric DNA Sensing with a Host-Guest FRET Pair.  Chem. Commun. 2019, 55, 671–674.

258A)  W. Wang, X. Wang, C. Xiang, X. Zhou, D. Gabel, W. M. Nau, K. I. Assaf, H. Zhang, Orthogonal Molecular Recognition of Chaotropic and Hydrophobic Guests Enables Supramolecular ArchitecturesChemNanoMat2019, 5, 124–129.


257A)   S. Zhang, Z. Dominguez, K. I. Assaf, M. Nilam, T. Thiele, U. Pischel, U. Schedler, W. M Nau and A. Hennig. Precise Supramolecular Control of Surface Coverage Densities on Polymer Micro- and NanoparticlesChem. Sci.2018, DOI: 10.1039/C8SC03150A .

256A)  S. He, F. Biedermann, N. Vankova, L. Zhechkov, T. Heine, R. E. Hoffman, A. De Simone, T. T. Duignan, W. M. Nau. Cavitation energies can outperform dispersion interactionsNat. Chem.2018, .

255R)   K. I. Assaf and Werner M. Nau, The Chaotropic Effect as an Assembly Motif in ChemistryAngew. Chem. 2018130, 14164–14177. Angew. Chem. Int. Ed. 201857, 13968–13981.

254A)  M. H. Jacob, I. Ghosh, R. N. D’Souza, W. M. Nau. Two Orders of Magnitude Variation of Diffusion-Enhanced Förster Resonance Energy Transfer in Polypeptide Chains.  Polymers 201810, 1079.

253A)  H. S. El-Sheshtawy, S. Chatterjee, K. I. Assaf, M. N. Shinde, W. M. Nau, J. Mohanty, A Supramolecular Approach for Enhanced Antibacterial Activity and Extended Shelf-life of Fluoroquinolone Drugs with Cucurbit[7]uril. Rep., 201818, 13925.

252A)   M. A. Alnajjar, J. Bartelmeß, R. Hein, P. Ashokkumar, M. Nilam, W. M. Nau, K. Rurack, A. Hennig, Rational Design of Boron-dipyrromethene (BODIPY) Reporter Dyes for Cucurbit[7]urilBeilstein J. Org. Chem. 201814, 1961-1971.

251A)  J. Nekvinda, B. Grüner, D. Gabel, W. M. Nau, K. I. Assaf, Host‐Guest Chemistry of Carboranes: Synthesis of Carboxylate Derivatives and Their Binding to CyclodextrinsChem. Eur. J.2018, 24, 12970–12975.

250A)  M. H. Jacob , R. N. D’Souza, T. Schwarzlose, X. Wang, F. Huang, E. Haas, W. M. Nau. A Method-Unifying View on Loop Formation Kinetics in Peptide and Protein FoldingJ. Phys. Chem. B, 2018122, 4445–4456.

249A)  G. H. Aryal, R. ViK, K. I. Assaf, K. W. Hunter, L. Huang, J. Jayawickramarajah, W. M. Nau. Structural Effects on Guest Binding in Cucurbit[8]uril‐Perylenemonoimide Host‐Guest ComplexesChemistrySelect, 2018, 3, 4699-4704.

248C)  W.-J. Wang, X. Wang, J. Cao, J. Liu, B. Qi, X. Zhou, S. Zhang, D. Gabel, W. M Nau, K. I. Assaf, H. Zhang. The Chaotropic Effect as an Orthogonal Assembly Motif for Multi-Responsive Dodecaborate-Cucurbituril Supramolecular NetworksCommun201854, 2098-2101. (Featured on the back cover page)

247C) K. I. Assaf, M. A. Alnajjar and W. M. Nau. Supramolecular Assemblies through Host–Guest Complexation between Cucurbiturils and an Amphiphilic Guest MoleculeChem. Commun. 201854, 1734-1737.


246A) A. I. Lazar, J. Rohacova, W. M. Nau, “Comparison of Complexation-Induced pKa Shifts in the Ground and Excited State of Dyes as Well as Different Macrocyclic Hosts and Their Manifestation in Host-Retarded Excited-Dye Deprotonation“, J. Phys. Chem. B,  2017, 121, 11390–11398.

245A)   K. I. Assaf, M. Florea, J. Antony, N. M. Henriksen, J. Yin, A. Hansen, Z.-w. Qu, R. Sure, D. Klapstein, M. K. Gilson, S. Grimme, W. M. Nau, “The HYDROPHOBE Challenge: A Joint Experimental and Computational Study on the Host-Guest Binding of Hydrocarbons to Cucurbiturils Allowing Explicit Evaluation of Guest Hydration Free Energy Contributions“, J. Phys. Chem. B,  2017, 121, 11144–11162.

244C) S. Peng, A. Barba-Bon, Y.-C. Pan, W. M. Nau, D.-S. Guo, A. Hennig, “Phosphorylation-Responsive Membrane Transport of Peptides”Angew. Chem. Int. Ed. 201756, 15742-15745; “Phosphorylierung reguliert den Membrantransport von Peptiden”Angew. Chem. 2017129, 15948-15951.

243C) A. Stahl, A. I. Lazar, V. N. Muchemu, W. M. Nau, M. S. Ullrich, A. Hennig, “A Fluorescent Supramolecular Chemosensor to Follow Steroid Depletion in Bacterial Cultures”Anal. Bioanal. Chem. 2017409, 6485-6494.

242A)  A. MukhopadhyayT. Hossen. GhoshA. KonerW. M. NauK. SahuJ. N. Moorthy“Helicity-Dependent Regiodifferentiation in the Excited-State Quenching and Chiroptical Properties of Inward/Outward Helical Coumarins”.Chem. Eur.J. 20123, 14797-14805.

241C) G. H. Aryal, K. I. Assaf, L. Huang, W. M. Nau, K. W. Hunter, “Intracavity Folding of a Perylene Dye Affords a High-Affinity Complex with Cucurbit[8]uril“Chem. Commun.201753, 9242-9245.

240A)  A.-M. Resmerita, K. I. Assaf, A. I. Lazar, W. M. Nau, A. Farcas, “Polyrotaxanes Based on PEG-Amine with Cucurbit[7]uril, α-Cyclodextrin and its tris-O-methylated Derivative“, Eur. Polym. J.201793, 323-333.

239 A)  X. WangY. WangH. HeX. MaQ. ChenS. ZhangB. GeS. WangW. M. Nau F. Huang“ Deep-Red Fluorescent Gold Nanoclusters for Nucleoi Staining: Real-Time Monitoring of the Nucleolar Dynamics in Reverse Transformation of Malignant Cells”. ACS Appl. Mat. Interf. 20179, 17799-17806.

238C) M. Nilam, A. Hennig, W. M. Nau, K. I. Assaf, “Gold Nanoparticle Aggregation Enables Colorimetric Sensing Assays for Enzymatic Decarboxylation”Anal. Methods 20179, 2784-2787.

237C)   S. M. Eiyrilmez, E. Bernhardt, J. Z. Dávalos, M. Lepšík, P. Hobza, K. I. Assaf, W. M. Nau, J. Holub, J. M. Oliva, J. Fanfrlíka, D. Hnyke, “Binary Twinned-icosahedral [B21H18]− Interacts with Cyclodextrins as a Precedent for its Complexation with other Organic Motifs“Phys. Chem. Chem. Phys., 201719, 11748-11752.

236C) K. I. Assaf, A. Hennig, S. Peng, D.-S. Guo, D. Gabel, W. M. Nau, “Hierarchical Host-Guest Assemblies Formed on Dodecaborate-Coated Gold Nanoparticles”Chem. Commun. 201753, 4616-4619.

235A) M. Nilam, P. Gribbon, J. Reinshagen, K. Cordts, E. Schwedhelm, W. M. Nau, A. Hennig, “A Label-Free Continuous Fluorescence-based Assay for Monitoring Ornithine Decarboxylase Activity with a Synthetic Putrescine Receptor”SLAS Discovery 201722, 906-914.


234A) A. I. Lazar, F. Biedermann, K. R. Mustafina, K. I. Assaf, A. Hennig, W. M. Nau, “Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications”J. Am. Chem. Soc. 2016138, 13022-13029.

233A) A. Farcas, K. I. Assaf, A. Resmerita, S. Cantin, M. Balan, P. Aubert, W. M. Nau, “Cucurbit[7]uril-based fluorene polyrotaxanes”Eur. Polym. J. 201683, 256–264.

232A) K. I. Assaf, D. Gabel, W. Zimmermann, W. M. Nau, “High-Affinity Host-Guest Chemistry of Large-Ring Cyclodextrins” , Org. Biomol. Chem.2016, DOI: 10.1039/C6OB01161F .

231C) X. Wang, H. He, Y. Wang, J. Wang, X. Sun, H. Xu, W. M Nau, X. Zhang, F. Huang. “Active tumor-targeting luminescent gold clusters with efficient urinary excretion“, Chem. Commun. 201652, 9232-9235.

230C) A. F. Eftaiha, F. Alsoubani, K. I. Assaf, W. M. Nau, C. Troll, A. K. Qaroush, “Chitin-Acetate/DMSO as a Supramolecular Green CO2-Phile“, RSC Adv. 20166, 22090-22093.

229C) K. I. Assaf, O. Suckova, N. Al-Danaf, V. von Glasenapp, D. Gabel, W. M. Nau, “Dodecaborate-Functionalized Anchor Dyes for Cyclodextrin-Based Indicator Displacement Applications“, Org. Lett. 201618, 932-935.

228A) N. Al Danaf, R. Abi Melhem, K. I. Assaf, W. M. Nau, D. Patra, “Photophysical Properties of Neutral and Dissociated Forms of Rosmarinic Acid“, J. Lumin. 2016175, 50-56.

227A) D.-S. Guo, V. D. Uzunova, K. I. Assaf, A. I. Lazar, Y. Liu, W. M. Nau, “Inclusion of Neutral Guests by Water-Soluble Macrocyclic Hosts – A Comparative Thermodynamic Investigation with Cyclodextrins, Calixarenes, and Cucurbiturils”Supramol. Chem. 201628, 384-395.

226A) N. Saleh, M. B. Al-Handawi, M. S. Bufaroosha, K. I. Assaf, W. M. Nau, “Tuning Protonation States of Tripelennamine Antihistamines by Cucurbit[7]uril”J. Phys. Org. Chem. 201629, 101-106.


225A)    S. T. J. Ryan, R. M. Young, J. J. Henkelis, N. Hafezi, N. A. Vermeulen, A. Hennig, E. J. Dale, Y. Wu, M. D. Krzyaniak, A. Fox, W. M. Nau, M. R. Wasielewski, J. F. Stoddart, O. A Scherman, “Energy and Electron Transfer Dynamics within a Series of Perylene Diimide/Cyclophane Systems”J. Am. Chem. Soc. 2015137, 15299-15307.

224C)   K. I. Assaf, M. S. Ural, F. Pan, T. Georgiev, S. Simova, K. Rissanen, D. Gabel, W. M. Nau, “Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin”Angew. Chem. Int. Ed. 201554, 6852-6856. (Featured as back cover)

223C)  V. R. de la Rosa, W. M. Nau and R. Hoogenboom, “Thermoresponsive Interplay of Water Insoluble Poly(2-alkyl-2-oxazoline)s Composition and Supramolecular Host-huest Interactions” Int.J.Mol.Sci. 201516, 7428-7444.

222A)  V. R. de la Rosa, W. M. Nau and R. Hoogenboom, “Tuning Temperature Responsive Poly(2-alkyl-2-oxazoline)s by Supramolecular Host-Guest Interactions”Org. Biomol. Chem. 201513, 3048-3057.

221C)  F. Biedermann, D. Hathazi and W. M. Nau, “Associative Chemosensing by Fluorescent Macrocycle-Dye Complexes – A Versatile Enzyme Assay Platform Beyond Indicator Displacement”Chem. Commun. 201551, 4977-4980.

220A)  C. P. Carvalho, A. Norouzy, V. Ribeiro, W. M. Nau and U. Pischel, “Cucurbiturils as supramolecular inhibitors of DNA restriction by type II endonucleases”Org. Biomol. Chem. 201513, 2866-2869.

219A)  A. Farcas, A.-M. Resmerita, P.-H. Aubert, I. Ghosh, S. Cantin, W. M. Nau, “Synthesis, photophysical and morphological properties of azomethine persylilated α-cyclodextrin main-chain polyrotaxane”Macromol. Chem. Phys. 2015, doi: 10.1002/macp.201400543 .

218A)   A. Farcas, P.-H.  Aubert, J. Mohanty, A. I. Lazar, S. Cantin, W. M. Nau, “Molecular wire formation from poly[2,7-(9,9-dioctylfluorene)-alt-(5,5`-bithiophene/ cucurbit[7]uril)] polyrotaxane copolymer”Eur. Polym. J.201562, 124-129.

217A)   A. Norouzy, K. I. Assaf, S. Zhang, M. H. Jacob, W. M. Nau, “Coulomb Repulsion in Short Polypeptides”J. Phys. Chem2015119, 33-43.

216R)  K. I. Assaf and W. M. Nau, “Cucurbiturils: From Synthesis to High-Affinity Binding and Catalysis”Chem. Soc. Rev. 201544, 394-418. (Featured on front cover page)

215C)   A. Norouzy, Z. Azizi, W. M. Nau, “Indikatorverdrängungsassays in lebenden Zellen”Angew. Chem. 2015127, 804-808; “Indicator Displacement Assays inside Live Cells”Angew. Chem. Int. Ed201554, 792-795.

214A)   M. Sayed, F. Biedermann, V. D. Uzunova, K. I. Assaf, A. C. Bhasikuttan, H. Pal, W. M. Nau, J. Mohanty, “Triple Emission of p-Dimethylaminobenzonitrile – Cucurbit[8]uril Triggers the Elusive Excimer Emission”Chem. Eur. J. 201521, 691-696.


213R)   A. Norouzy, W. M. Nau, “Synthetic Macrocyclic Receptors as Tools in Drug Delivery and Drug Discovery”Drug Target Review 2014.

212A)   I. Ghosh, A. Mukhopadhyay, A. L. Koner, S. Samanta, W. M. Nau and J. N. Moorthy, “Excited-state properties of fluorenones: Influence of substituents, solvent and macrocyclic encapsulation” Phys. Chem. Chem. Phys. 201416, 16436-16445.

211A)   K. I. Assaf and W. M. Nau, “Cucurbiturils as fluorophilic receptors”, Supramol. Chem. 201426, 657-669.

210R)   F. Biedermann, W. M. Nau and H.-J. Schneider, “The Hydrophobic Effect Revisited-Studies with Supramolecular Complexes Imply High-Energy Water as a Noncovalent Driving Force”, Angew. Chem. Int. Ed. 2014, 53, 11158-11171.

209C)   J. Vázquez, P. Remón, R. N. Dsouza, A. I. Lazar, J. F. Arteaga, W. M. Nau and U. Pischel, “A Simple Assay for Quality Binders to Cucurbiturils”, Chem. Eur. J. 201420, 9897-9901.

208A)   S. T. J. Ryan, J. del Barrio, I. Ghosh, F. Biedermann, A. I. Lazar, Y. Lan, R. J. Coulston, W. M. Nau, and O. A. Scherman, “Efficient Host-Guest Energy Transfer in Polycationic Cyclophane-Perylene Diimide Complexes in Water”, J. Am. Chem. Soc. 2014136, 9053-9060.

207R)   G. Ghale, W. M. Nau, “Dynamically Analyte-Responsive Macrocyclic Host–Fluorophore Systems”Acc. Chem. Res201447, 2150-2159.

206C)   F. Biedermann, W. M. Nau, “Noncovalent Chirality Sensing Ensembles for Detection and Reaction Monitoring of Amino Acids, Peptides, Proteins, and Aromatic Drugs”Angew. Chem. Int. Ed. 201453, 11158-11171.

205R)   B. Mizaikoff, M. Lämmerhofer, J. Popp, S. He, W. M. Nau, K. Leopold, C. Kranz, J. W. Einax, “Trendbericht Analytische Chemie 2012/2013”, Nachr. Chem. 201462, 407-414.

204C)   G. Ghale, A. G. Lanctôt, H. T. Kreissl, M. H. Jacob, H. Weingart, M. Winterhalter, W. M. Nau, “Chemosensing Ensembles for Monitoring Biomembrane Transport in Real Time“Angew. Chem. Int. Ed. 201453, 2762-2765.


203A)   F. Biedermann, M. Vendruscolo, O. A. Scherman, A. De Simone, W. M. Nau, “Cucurbit[8]uril and Blue-box: High-energy Water Release Overwhelms Electrostatic Interactions”, J. Am. Chem. Soc. 2013135, 14879-14888.

202A)   V. Francisco, A. Piñeiro, W. M. Nau, L. García-Río, “The “true” affinities of inorganic metal cations to p-sulfonatocalix[4]arene: a thermodynamic study at neutral pH reveals a pitfall due to salt effects in microcalorimetry”, Chem. Eur. J. 201319, 17809-17820.

201A)   N. Abdali, E. Barth, A. Norouzy, R. Schulz, W. M. Nau, U. Kleinekathöfer, A. Tauch, R. Benz, “Corynebacterium jeikeium jk0268 constitutes for the 40 amino acid long PorACj, which forms a homooligomeric and anion-selective cell wall channel”, PLoS ONE 20138, e75651.

200A)   T.-C. Lee, E. Kalenius, A. I. Lazar, K. I. Assaf, N. Kuhnert, C. H. Grün, J. Jänis, O. A. Scherman and W. M. Nau, “Chemistry inside molecular containers in the gas phase”Nature Chem. 20135, 376-382.

199R)   N. Saleh, I. Ghosh, W. M. Nau, “Cucurbiturils in Drug Delivery and for Biomedical Applications in Supramolecular Systems in Biomedical Fields” H. J. Schneider, Ed., RSC Publishing, 2013, in press.

198A)   F. Biedermann, W. M. Nau, “Fässerweise Moleküle – Natürliche und synthetische Makrozyklen finden vielfältige Anwendungen in der Wirkstofforschung und Analytik”labor&more 2013, 30-35.

197A)   M. H. Jacob, R. N. Dsouza, I. Ghosh, A. Norouzy, T. Schwarzlose, W. M. Nau, “Diffusion-enhanced FRET and the Effects of External Quenchers and the Donor Quantum Yield”, J. Phys. Chem. B. 2013117, 185–198.


196A)   H. S. El-Sheshtawy, B. S. Bassil, K. I. Assaf, U. Kortz, W. M. Nau, “Halogen Bonding Inside a Molecular Container”, J. Am. Chem. Soc. 2012134, 19935-19941.

195A)   R. Sharma, M. Florea, W. N. Nau, K. Swaminathan, “Validation of Drug-Like Inhibitors against Mycrobacterium Tuberculosis L-aspatate α-decarboxylase Using Nuclear Magnatic Resonance (1H NMR)”, PLOS One 20127, e45947.

194A)   F. Biedermann, V. D. Uzunova, O. A. Scherman, W. M. Nau, A. De Simone, “Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils”J. Am. Chem. Soc. 2012134, 15318-15323.

193A)   S. Joshi, I. Ghosh, S. Pokhrel, L. Mädler, W. M. Nau, “Interactions of Amino Acids and Polypeptides with Metal Oxide Nanoparticles Probed by Fluorescent Indicator Adsorption and Displacement”, ACS Nano 20126, 5668-5679.

192C)   F. Biedermann, E. Elmalem, I. Ghosh, W. M. Nau, O. A. Scherman, “Strongly fluorescent, switchable perylene-bisdiimide (PDI) host-guest complexes with cucurbit[8]uril in water”Angew. Chem. Int. Ed. 201251, 7739-7743. (featured on cover page)

191C)   A. Farcas, I. Ghosh, W. M. Nau, “Effect of α-cyclodextrin on the optical and surface-morphological properties of pyrene-triazole azomethine oligomers”, Chem. Phys. Lett. 2012535, 120-125.

190R)   I. Ghosh, W. M. Nau, “The strategic use of supramolecular pKa shifts to enhance the bioavailability of drugs”Adv. Drug. Deliv. Rev. 201264, 764-783.

189R)   B. Mizaikoff, M. Lämmerhofer, J. A. C. Broekaert, J. Popp, B. Lendl, K. Leopold, F. W. Scheller, A. Yarman, S. Schumacher, N. Plumeré, A. Hennig, W. M. Nau, C. Kranz, J. W. Einax, “Trendbericht Analytische Chemie 2010/2011”, Nachr. Chem. 201260, 406-420.

188A)   G. Ghale, N. Kuhnert, W. M. Nau, “Monitoring Stepwise Proteolytic Degradation of Peptides by Supramolecular Domino Tandem Assays and Mass Spectrometry for Trypsin and Leucine Aminopeptidase”, Nat. Prod. Comm. 20127, 343-348.

187A)   M. Florea, S. Kudithipudi, A. Rei, M. José González-Álvarez, A. Jeltsch, W. M. Nau, “A Fluorescence-Based Supramolecular Tandem Assay for Monitoring Lysine Methyltransferase Activity in Homogeneous Solution”, Chem. Eur. J. 201218, 3521-3528.

186A)   R. N. Dsouza, A. Hennig, W. M. Nau, “Supramolecular Tandem Enzyme Assays”, Chem. Eur. J. 201218, 3444-3459.

185A)   S. Abraham, I. Ghosh, W. M. Nau, C. Chesta, S. J. Pas, A. J. Hill, R. G. Weiss, “In-cage and out-of-cage combinations of benzylic radical pairs in the glassy and melted states of poly(alkyl methacrylate)s”, Photochem. Photobiol. Sci. 201211, 914-924.

184R)   M. H. Jacob, W. M. Nau, “Short-distance FRET Applied to the Polypeptide Chain” in Folding, Misfolding and Nonfolding of Peptides and Small Proteins, R. Schweitzer-Stenner, Ed., John Wiley & Sons, Inc., Hoboken, New Jersey, U.S.A., 2012, 99-126.


183R)   R. N. Dsouza, U. Pischel, W. M. Nau, “Fluorescent Dyes and their Supramolecular Host-Guest Complexes with Macrocycles in Aqueous Solution”Chem. Rev. 2011111, 7941–7980.

182C)   M. Florea, W. M. Nau, “Strong Binding of Hydrocarbons to Cucurbituril Probed by Fluorescent Dye Displacement: A Supramolecular Gas-Sensing Ensemble”, Angew. Chem. 2011,123,9510-9514; Angew. Chem. Int. Ed. 201150, 9338-9342.

181C)   N. Saleh, Y. A. Al-Soud, L. Al-Kaabi, I. Ghosh, and W. M. Nau, “A Coumarin-based Fluorescent PET Sens or Utilizing Supramolecular pKa Shifts”, Tetrahedron Lett. 201152, 5249-5244.

180E)   W. Nau, A. I. Lazar, S. Joshi, “Book Review: Artificial Receptors for Chemical Sensors”, Angew. Chem. 2011123, 8622-8623, Angew. Chem. Int. Ed. 201150, 8472-8473.

179E)   W. Nau, “Book Review: Modern Molecular Photochemistry of Organic Molecules”, ChemPhysChem 201112, 2496-2497.

178A)   N. Saleh, M. A. Meetani, L. Al-Kaabi, I. Ghosh, W. M. Nau, “Effect of Cucurbit[n]urils on Tropicamide and Potential Application in Ocular Drug Delivery”, Supramol. Chem. 201123, 654-661.

177C)   C. Parente Carvalho, Vanya D. Uzunova, J. P. da Silva, W. M. Nau, U. Pischel, “A Photoinduced pH Jump Applied to Drug Release from Cucurbit[7]uril”, Chem. Commun. 201147, 8793-8795.

176R)   R. N. Dsouza, W. M. Nau, U. Pischel, “Complexation of Fluorescent Dyes by Macrocyclic Hosts” in Supramolecular Effects on Photochemical and Photophysical Processes, V. Ramamurthy, Y. Inoue, Eds., John Wiley & Sons, Inc., Hoboken, New Jersey, U.S.A. 2011, 87-114.

175A)   D.-S. Guo, V. D. Uzunova, X. Su, Y. Liu, W. M. Nau, “Operational calixarene-based fluorescent sensing systems for choline and acetylcholine and their application to enzymatic reactions”, Chem. Sci. 20112, 1722-1734.

174R)   W. M. Nau, M. Florea, K. I. Assaf, “Deep Inside Cucurbiturils: Physical Properties and Volumes of their Inner Cavity Determine the Hydrophobic Driving Force for Host–Guest Complexation”, Isr. J. Chem. 201151, 559-577.

173A)   W. M. Nau, O. A. Scherman, “The World of Cucurbiturils – From Peculiarity to Commodity (Guest Editorial)”, Isr. J. Chem. 201151, 492-494; featured on cover page.

172A)   G. Ghale, V. Ramalingam, A. R. Urbach, W. M. Nau, “Determining Protease Substrate Selectivity and Inhibition by Label-Free Supramolecular Tandem Enzyme Assays”, J. Am. Chem. Soc. 2011133, 7528-7535.

171C)   H. S. El-Sheshtawy, U. Pischel, W. M. Nau, “Solvent Polarity Affects H Atom Abstractions from C–H Donors”, Org. Lett. 201113, 2694-2697.

170A)   J. N. Moorthy, S. Samanta, A. L. Koner, W. M. Nau, “Steady-state photochemistry (Pschorr cyclization) and Nanosecond Transient Absorption Spectroscopy of Twisted 2-Bromoaryl Ketones”, Pure Appl. Chem. 201183, 841-860.

169A)   A. Farcas, I. Ghosh, V. C. Grigoras, I. Stoica, C. Peptu, W. M. Nau, “Effect of Rotaxane Formation on the Photophysical, Morphological, and Adhesion Properties of Poly[2,7-(9,9-Dioctylfluorene)-alt-(5,5′-Bithiophene)] Main Chain Polyrotaxanes”, Macromol. Chem. Phys. 2011212, 1022-1031.

168A)   A. L. Koner, I. Ghosh, N. Saleh, W. M. Nau, “Supramolecular Encapsulation of Benzimidazole-Derived Drugs by Cucurbit[7]uril”, Can. J. Chem. 201189, 139-147.

167C)   A. L. Koner, C. Márquez, M. H. Dickman, W. M. Nau, “Chemoselektive Photoreaktionen mithilfe von Übergangsmetallen in Cucurbiturilen”, Angew. Chem. 2011123, 567-571; “Transition Metal-Promoted Chemoselective Photoreactions at the Cucurbituril Rim”, Angew. Chem. Int. Ed. 201150, 545-548; featured on cover page.


166A)   D. Verbaro, I. Ghosh, W. M. Nau, R. Schweitzer-Stenner, “Discrepancies between Conformational Distributions of a Polyalanine Peptide in Solution Obtained from Molecular Dynamics Force Fields and Amide I′ Band Profiles”, J. Phys. Chem. B2010, 114, 17201-17208.

165A)   J. Mohanty, K. Jagtap, A. K. Ray, W. M. Nau, H. Pal, “Molecular Encapsulation of Fluorescent Dyes Affords Efficient Narrow-band Dye Laser Operation in Water”, ChemPhysChem 201011, 3333-3338.

164A)   R. Meyer, A. F.-P. Sonnen and W. M. Nau, “Phase-Dependent Lateral Diffusion of α-Tocopherol in DPPC Liposomes Monitored by Fluorescence Quenching”, Langmuir 201026, 14723-14729.

163R)   W. M. Nau, “Supramolecular Capsules: Under Control”, Nature Chemistry 20102, 248-250.

162A)   I. Ghosh, N. Saleh and W. M. Nau, “Selective time-resolved binding of copper (II) by pyropheophorbide-a methyl ester”, Photochem. Photobiol. Sci. 20109, 649-654.

161C)   U. Pischel, V. D. Uzunova, P. Remón, W. M. Nau, “Supramolecular Logic with Macrocyclic Input and Competitive Reset”, Chem. Commun. 2010, 46, 2635-2637.

160A)   V. D. Uzunova, C. Cullinane, K. Brix, W. M. Nau, and A. I. Day, “Toxicity of Cucurbit[7]uril and Cucurbit[8]uril: An Exploratory in vitro and in vivo Study”, Org. Biomol. Chem20108, 2037-2042.

159A)   J. Cui, V. D. Uzunova, D.-S. Guo, K. Wang, W. M. Nau, Y. Liu, “Effect of Lower-Rim Alkylation of p-Sulfonatocalix[4]arene on the Thermodynamics of Host–Guest Complexation”, Eur. J. Org. Chem. 2010, 1704-1710.

158A)   M. Florea and W. M. Nau, “Implementation of Anion-Receptor Macrocycles in Supramolecular Tandem Assays for Enzymes Involving Nucleotides as Substrates, Products, and Cofactors”, Org. Biomol. Chem. 20108, 1033-1039.


157A)   R. Meyer, X. Zhang and W. M. Nau, “Effect of bridgehead substitution on the fluorescence quenching of 2,3diazabicyclo[2.2.2]oct-2-enes by solvents and antioxidants”, Photochem. Photobiol. Sci. 20098, 1694-1700.

156A)    M. Shaikh, S. D. Choudhury, J. Mohanty, A. C. Bhasikuttan, W. M. Nau, Haridas Pal, “Restricted Excited State Proton Transfer of 2-(2′-Hydroxyphenyl)benzimidazole in a Macrocyclic Cucurbit[7]uril Host Cavity: Dual Emission Behavior and pKa Shift”, Chem. Eur. J. 200915, 12362-12370.

155A)   A. Farcas, N. Jarroux, I. Ghosh, P. Guégan, W. M. Nau, V. Harabagiu, “Synthesis and Characterization of Pyrene-Linked Conjugated Azomethine Polyrotaxanes”, Macromol. Chem. Phys. 2009210, 1440-1449.

154A)   W. M. Nau, G. Ghale, A. Hennig, H. Bakirci, D. M. Bailey, “Substrate-Selective Supramolecular Tandem Assays: Monitoring Enzyme Inhibition of Arginase and Diamine Oxidase by Fluorescent Dye Displacement from Calixarene and Cucurbituril Macrocycles”, J. Am. Chem. Soc. 2009,131, 11558-11570.

153A)   C. Klöck, R. N. Dsouza, W. M. Nau, “Cucurbituril-mediated Supramolecular Acid Catalysis”, Org. Lett. 200911, 2595-2598.

152A)    J. N. Moorthy, A. L. Koner, S. Samanta, A. Roy, W. M. Nau, “Modulation of Spectrokinetic Properties of o-Quinonoid Reactive Intermediates by Electronic Factors: Time-Resolved Laser Flash and Steady-State Photolysis Investigations of Photochromic of 6- and 7- Arylchromenes”, Chem. Eur. J. 200914, 4289-4300.

151C)   W. M. Nau, “Autoren-Profil”, Angew. Chem. 2009121, 1209; “Author Profile”, Angew. Chem. Int. Ed. 200948, 1187.


150A)    A. Farcas, I. Ghosh, N. Jarroux, V. Harabagiu, P. Guégan, W. M. Nau, “Morphology and Properties of a Polyrotaxane based on gamma-Cyclodextrin and a Polyfluorene Copolymer”, Chem. Phys. Lett. 2008465, 96-101.

149A)    J. N. Moorthy, S. Samanta, A. L. Koner, S. Saha, W. M. Nau, “Intramolecular O-H–O Hydrogen Bond-Mediated Reversal in the Partitioning of Conformationally-Restricted Triplet 1,4-Biradicals and Amplification of Diastereo-differentiation in their Lifetimes”, J. Am. Chem. Soc. 2008130, 13608–13617.

148A)    N. Saleh, Y. A. Al-Soud, W. M. Nau, “Novel fluorescent pH sensor based on coumarin with piperazine and imidazole substituents”, Spectrochim. Acta A 200871, 818-822.

147A)    A. Praetorius, D. M. Bailey, T. Schwarzlose, W. M. Nau, “Design of a Fluorescent Dye for Indicator Displacement from Cucurbiturils: A Macrocycle-Responsive Fluorescent Switch Operating through a pKa Shift”, Org. Lett. 200810, 4089–4092.

146A)    R. N. Dsouza, W. M. Nau, “Triple Molecular Recognition as a Directing Element in the Formation of Host-Guest Complexes with p-sulfonatocalix[4]arene (CX4) and beta-cyclodextrin”, J. Org. Chem. 200873, 5305–5310.

145C)    M. Shaikh, J. Mohanty, A. C. Bhasikuttan, V. D. Uzunova, W. M. Nau, H. Pal, “Salt-induced Guest Relocation from a Supramolecular Cavity into a Biomolecular Pocket: Interplay between Cucurbit[7]uril and Albumin”, Chem. Commun. 2008, 3681-3683.

144A)    D. M. Bailey, A. Hennig, V. D. Uzunova, W. M. Nau, “Supramolecular Tandem Enzyme Assays for Multiparameter Sensor Arrays and Enantiomeric Excess Determination of Amino Acids”, Chem. Eur. J. 200814, 6069–6077. (selected as VIP paper; featured on front cover page)

143C)    N. Saleh, A. L. Koner, W. M. Nau, “Activation and Stabilization of Drugs by Supramolecular pKa Shifts: Drug Delivery Applications Tailored for Cucurbiturils”, Angew. Chem. 2008120, 5478–5481; “Activation and Stabilization of Drugs by Supramolecular pKa Shifts: Drug Delivery Applications Tailored for Cucurbiturils”, Angew. Chem. Int. Ed. 200847, 5398–5401.

142R)    W. M. Nau, M. Florea, H. Sahoo, H. Bakirci, A. Hennig, D. Bailey, “Nano-TRF und Tandem Assays fьr HTS und Multiparameteranalytik” in: “Multiparameteranalytik – Methoden, Applikationen, Perspektiven”, K. Conrad, W. Lehmann, U. Sack, U. Schedler, Eds., Pabst Verlag, Lengerich, 2008, 147-162.

141R)    W. M. Nau, A. Hennig, A. L. Koner, “Squeezing Fluorescent Dyes into Nanoscale Containers – The Supramolecular Approach to Radiative Decay Engineering” in: “Fluorescence of Supermolecules, Polymers, and Nanosystems”, M. N. Berberan-Santos, Ed., Springer Ser. Fluoresc., Volume 4, 2008, 185-211.

140A)    M. Shaikh, J. Mohanty, P. K. Singh, W. M. Nau, H. Pal, “Complexation of Acridine Orange by Cucurbit[7]uril and beta-Cyclodextrin: Photophysical Effects and pKa Shifts”, Photochem. Photobiol. Sci. 20087, 408-414; (featured on front cover page)


139A)    H. Sahoo, A. Hennig, M. Florea, D. Roth, T. Enderle, W. M. Nau, “Single-Label Kinase and Phosphatase Assay for Tyrosine Phosphorylation Using Nanosecond Time-Resolved Fluorescence Detection”, J. Am. Chem. Soc. 2007129, 15927-15934.

138A)    T. Nam, C. L. Rector, H. Kim, A. F.-P. Sonnen, R. Meyer, W. M. Nau, J. Atkinson, J. Rintoul, D. A. Pratt, N. A. Porter, “Tetrahydro-1,8-Naphthyridinol Analogues of alpha-Tocopherol as Antioxidants in Lipid Membranes and Low Density Lipoproteins”, J. Am. Chem. Soc. 2007129, 10211-10219.

137A)    H. Sahoo, D. Roccatano, A. Hennig, W. M. Nau, “A 10-Å Spectroscopic Ruler Applied to Short Polyprolines”, J. Am. Chem. Soc. 2007129, 9762-9772.

136C)    A. Hennig, H. Bakirci, W. M. Nau, “Label-Free Continuous Enzyme Assays based on Macrocyclic Fluorescent Dye Complexes”, Nat. Methods20074, 629-632, (featured on front cover page)

135C)    A. L. Koner, U. Pischel, W. M. Nau, “Kinetic Solvent Effects on Hydrogen Abstraction Reactions”, Org. Lett. 20079, 2899-2902.

134A)    A. L. Koner, J. Schatz, W. M. Nau, U. Pischel, “Selective Sensing of Citrate by a Supramolecular 1,8-Naphthalimide/Calix[4]arene Assembly via Complexation-modulated pKa Shifts in a Ternary Complex”, J. Org. Chem. 200772, 3889-3895.

133C)    A. C. Bhasikuttan, J. Mohanty, W. M. Nau, H. Pal, “Efficient Fluorescence Enhancement and Cooperative Binding of an Organic Dye in a Supra-bimolecular Host-protein assembly”, Angew. Chem. Int. Ed. 200746, 4120-4122; Angew. Chem. 2007119, 4198-4200.

132A)    C. A. Chesta, J. Mohanty, W. M. Nau, U. Bhattacharjee, R. G. Weiss, “New Insights into the Mechanism of Triplet Radical-pair Combinations. The Persistent Radical Effect Masks the Distinction between In-cage and Out-of-cage Processes”, J. Am. Chem. Soc. 2007129, 5012-5022.

131C)    A. Hennig, G. Ghale, W. M. Nau, “Effects of Cucurbit[7]uril on Protease Activity”, Chem. Commun. 2007, 1614-1616.

130A)    D. Roccatano, H. Sahoo, M. Zacharias, W. M. Nau, “Temperature Dependence of Looping Rates in a Short Peptide”, J. Phys. Chem. B 2007111, 2639-2646.

129A)    A. Hennig, T. Schwarzlose, W. M. Nau, “Bridgehead Carboxy-Substituted 2,3-Diazabicyclo[2.2.2]oct-2-enes: Synthesis, Fluorescent Propeties, and Host-Guest Complexation”, ARKIVOC 2007(viii), 341-357.

128A)    H. Sahoo, W. M. Nau, “Phosphorylation-Induced Conformational Changes in Short Peptides Probed by Fluorescence Resonance Energy Transfer in the 10-Å Domain”, ChemBioChem 20078, 567-573.

127C)    J. Mohanty, H. Pal, A. K. Ray, S. Kumar, W. M. Nau, “Supramolecular Dye Laser with Cucurbit[7]uril in Water”, ChemPhysChem 20078, 54-56.

126A)    A. Hennig, M. Florea, D. Roth, T. Enderle, W. M. Nau, “Design of Peptide Substrates for Nanosecond Time-Resolved Fluorescence Assays of Proteases: 2,3-Diazabicyclo[2.2.2]oct-2-ene as a Noninvasive Fluorophore”, Anal. Biochem. 2007360, 255-265.

125A)    A. L. Koner, W. M. Nau, “Cucurbituril Encapsulation of Fluorescent Dyes”, Supramol. Chem. 200719, 55-66.


124C)    H. Bakirci, A. L. Koner, M. H. Dickman, U. Kortz, W. M. Nau, “Dynamically Self-Assembling Metalloenzyme Models Based on Calixarenes”, Angew. Chem. 2006118, 7560-7564; “Dynamically Self-Assembling Metalloenzyme Models Based on Calixarenes”, Angew. Chem. Int. Ed. 200645, 7400-7404.

123A)    J. N. Moorthy, A. L. Koner, S. Samanta, N. Singhal, W. M. Nau, R. G. Weiss, “Diastereomeric Discrimination in the Lifetimes of Norrish Type II Triplet 1,4-Biradicals and Stereo-Controlled Partitioning of their Reactivity (Yang Cyclization vs Type II Elimination)”, Chem. Eur. J. 200612, 8744-8749.

122A)    H. Sahoo, W. M. Nau, “Phosphorylation-Induced Rigidification of Peptides Probed by Time-Resolved Fluorescence Spectroscopy”, Ind. J. Rad. Res. 20063, 104-112.

121C)    H. Sahoo, D. Roccatano, M. Zacharias, W. M. Nau, “Distance Distributions of Short Polypeptides Recovered by Fluorescence Resonance Energy Transfer in the 10 Å Domain”, J. Am. Chem. Soc. 2006128, 8118-8119.

120A)   H. Sahoo, A. Hennig, W. M. Nau, “Temperature-Dependent Loop Formation Kinetics in Flexible Peptides Studied by Time-Resolved Fluorescence Spectroscopy”, Intern. J. Photoenergy 20068, 1-9.

119A)    H. Bakirci, A. L. Koner, T. Schwarzlose, W. M. Nau, “Analysis of Host-Assisted Guest Protonation Exemplified for p-Sulfonatocalix[4]arene – Towards Enzyme-Mimetic pKa Shifts”, Chem. Eur. J. 200612, 4799-4807.

118C)    A. Hennig, D. Roth, T. Enderle, W. M. Nau, “Fast Time-Resolved Fluorescence Protease Assays”, ChemBioChem. 20067, 733-737.

117A)    C. Vannesjö Lundgren, A. L. Koner, M. Tinkl, U. Pischel, W. M. Nau, “Reaction of Singlet-Excited 2,3-Diazabicyclo[2.2.2]oct-2-ene and tert-Butoxyl Radicals with Aryl-Substituted Benzofuranones”, J. Org. Chem. 200671, 1977-1983.

116A)    J. Mohanty, A. C. Bhasikuttan, W. M. Nau, H. Pal, “Host-Guest Complexation of Neutral Red with Macrocyclic Host Molecules: Contrasting pKa Shifts and Binding Affinities for Cucurbit[7]uril and beta-Cyclodextrin”, J. Phys. Chem. B 2006110, 5132-5138.

115A)    U. Pischel, D. Patra, A. L. Koner, W. M. Nau, “Investigation of Polar and Stereoelectronic Effects on Pure Excited-State Hydrogen Atom Abstractions from Phenols and Alkylbenzenes”,Photochem. Photobiol. 200682, 310-317.

114A)    H. Bakirci, W. M. Nau, “Fluorescence Regeneration as Signaling Principle for Choline and Carnitine Binding: A Refined Supramolecular Sensor System Based on a Fluorescent Azoalkane“, Adv. Funct. Mat. 200616, 237-242.


113R)    W. M. Nau, U. Pischel, “Photoreactivity of n,pi*-Excited Azoalkanes and Ketones” in Molecular and Supramolecular Photochemistry, V. Ramamurthy, K. S. Schanze, Eds., Volume 9, 2005, 75-129.

112A)    H. Bakirci, A. L. Korner, W. M. Nau, “Spherical Shape Complementarity as an Overriding Motif in the Molecular Recognition of Noncharged Organic Guests by p-Sulfonatocalix[4]arene: Complexation of Bicyclic Azoalkanes”, J. Org. Chem. 200570, 9960-9966.

111C)    H. Bakirci, A. L. Korner, W. M. Nau, “Binding of inorganic cations by p-sulfonatocalix[4]arene monitored through competitive fluorophore displacement in aqueous solution”, Chem. Commun. 2005, 5411-5413.

110A)    A. F.-P. Sonnen, H. Bakirci, T. Netscher, W. M. Nau, “Effect of Temperature, Cholesterol Content, and Antioxidant Structure on the Mobility of Vitamin E Constituents in Biomembrane Models Studied by Laterally Diffusion-Controlled Fluorescence Quenching”, J. Am. Chem. Soc. 2005127, 15575-15584.

109A)    N. Singhal, A. L. Koner, P. Mal, P. Venugopalan, W. M. Nau, J. N. Moorthy, “Diastereomer-Differentiating Photochemistry of beta-Arylbutyrophenones: Yang Cyclization versus Type II Elimination”, J. Am. Chem. Soc. 2005127, 14375-14382.

108A)    A. L. Koner, N. Singhal, W. M. Nau, J. N. Moorthy, “Substituent Electronic Effects on the Persistence and Absorption Spectra of (Z)-o-Xylylenols. A Nanosecond Laser Flash Photolysis Study”, J. Org. Chem.200570, 7439-7442.

107A)    F. Huang, W. M. Nau, “Photochemical Techniques for Studying the Flexibility of Polypeptides”, Res. Chem. Intermed.200531, 717-726.

106A)    H. Bakirci, W. M. Nau, “Chiral Discrimination in the Complexation of Heptakis(2,6-di-O-methyl)-beta-cyclodextrin with 2,3-Diazabicyclo[2.2.2]oct-2-ene Derivatives”, J. Photochem. Photobiol. A: Chem2005173, 340-348.

105A)    H. Bakirci, W. M. Nau, “Chiral Resolution through Precipitation of Diastereomeric Capsules in the Form of 2:1 beta-Cyclodextrin-Guest Complexes”, J. Org. Chem.200570, 4506-4509.

104A)    W. M. Nau, J. Mohanty, “Taming Fluorescent Dyes with Cucurbituril”, Intern. J. Photoenergy20057, 133-141.

103C)    J. Mohanty, W. M. Nau, “Ultrastable Rhodamine with Cucurbituril”, Angew. Chem.2005117, 3816-3820; “Ultrastable Rhodamine with Cucurbituril”, Angew. Chem. Int. Ed.200544, 3750-3754.

102A)    H. Bakirci, X. Zhang, W. M. Nau, “Induced Circular Dichroism and Structural Assignment of the beta-Cyclodextrin Inclusion Complexes of Bicyclic Azoalkanes”, J. Org. Chem.200570, 39-46.



101A)    F. Huang, R. R. Hudgins, W. M. Nau, “Primary and Secondary Structure Dependence of Peptide Flexibility Assessed by Fluorescence-Based Measurement of End-to-End Collision Rates”, J. Am. Chem. Soc. 2004126, 16665-16675.

100A)    J. Mohanty, W. M. Nau, “Refractive Index Effects on the Oscillator Strength and Radiative Decay Rate of 2,3-Diazabicyclo[2.2.2]oct-2-ene”, Photochem. Photobiol. Sci. 20043, 1026-1031.

99A)      D. Roccatano, W. M. Nau, M. Zacharias, “Structural and Dynamic Properties of CAGQW Peptide in Water: A Dynamics Simulation Study Using Different Force Fields”, J. Phys. Chem. B 2004108, 18734-18742.

98A)      C. Marquez, R. R. Hudgins, W. M. Nau, “The Mechanism of Host-Guest Complexation by Cucurbituril”, J. Am. Chem. Soc. 2004126, 5806-5816.

97A)      G. Gramlich, J. Zhang, W. M. Nau, “Diffusion of alpha-Tocopherol in Membrane Models: Probing the Kinetics of Vitamin E Antioxidant Action by Fluorescence in Real Time”, J. Am. Chem. Soc. 2004126, 5482-5492.

96A)      X. Wang, W. M. Nau, “Kinetics of End-to-End Collision in Short Single-Stranded Nucleic Acids”, J. Am. Chem. Soc. 2004126, 808-813.

95A)      U. Pischel, F. Huang, W. M. Nau, “Intramolecular singlet-singlet energy transfer in antenna-substituted azoalkanes”, Photochem. Photobiol. Sci. 20043, 305-310.

94A)      C. Marquez, F. Huang, W. M. Nau, “Cucurbiturils: Molecular Nanocapsules for Time-Resolved Fluorescence-based Assays”, IEEE Trans. Nanobiosci. 20043, 39-45.

93A)      C. Erb, K. Nau-Staudt, J. Flammer, W. M. Nau, “Ascorbic Acid as a Free Radical Scavenger in Porcine and Bovine Aqueous Humor”, Opth. Res. 200436, 38-42.


92C)      C. Marquez, U. Pischel, W. M. Nau, “Selective Fluorescence Quenching of 2,3-Diazabicyclo[2.2.2]oct-2-ene by Nucleotides “, Org. Lett. 20035, 3911-3914.

91A)      X. Wang, E. N. Bodunov, W. M. Nau, “Fluorescence Quenching Kinetics in Short Polymer Chains: Dependence on Chain Length”, Opt. Spectrosc. 200395, 560-570.

90C)      F. Huang, W. M. Nau, “A Conformational Flexibility Scale for Amino Acids in Peptides”, Angew. Chem. 2003115, 2371-2374; ” A Conformational Flexibility Scale for Amino Acids in Peptides”, Angew. Chem. Int. Ed. 200342, 2269-2272.

89A)      W. M. Nau, F. Huang, X. Wang, H. Bakirci, G. Gramlich, C. Marquez, “Exploiting Long-Lived Molecular Fluorescence”, Chimia 200357, 161-167.


88C)      G. Gramlich, J. Zhang, W. M. Nau, “Increased Antioxidant Reactivity of Vitam C at low pH in Model Membranes”, J. Am. Chem. Soc. 2002124, 11252-11253.

87A)      D. Klapstein, U. Pischel, W. M. Nau, “Quenching of n,pi*-Excited States in the Gas Phase: Variations in Absolute Reactivity and Selectivity”, J. Am. Chem. Soc. 2002124, 11349-11357.

86A)      W. Adam, J. Hartung, H. Okamoto, S. Marquardt, W. M. Nau, U. Pischel, C. R. Saha-Möller, K. Spehar, “Photochemistry of N-Isopropoxy-Substituted 2-Pyridone and 2(3H)-Thiazoethione: Alkoxyl-Radical release (Spin Trapping, EPR and Transient Spectroscopy) and its Significance in the Photooxidative Induction of DNA Strand Breaks”, J. Org. Chem. 200267, 6041-6049.

85R)      A. Sinicropi, W. M. Nau, M. Olivucci, “Excited State Quenching via Unsuccessful Chemical Reactions”, Photochem. Photobiol. Sci. 20021, 537-546, (cover page).

84C)      U. Pischel, M. S. Galletero, H. Garcia, M. A. Miranda, W. M. Nau, “Photophysical properties and fluorescence quenching of 2,3-diazabicyclo[2.2.2]oct-2-ene in zeolites: Linear diffusion provides an explanation for non-monoexponential transient decay kinetics”, Chem. Phys. Lett. 2002359, 289-294.

83A)      W. Adam, M. A. Arnold, W. M. Nau, U. Pischel, C. R. Saha-Möller, “A Comparative Photomechanistic Study (Spin Trapping, EPR Spectroscopy, Transient Kinetics, Photoproducts) of Nucleoside Oxidation (dG and 8-oxodG) by Triplet-Excited Acetophenones and by the Radicals Generated from alpha-Oxy-Substituted Derivatives through Norrish-Type I Cleavage”, J. Am. Chem. Soc. 2002124, 3893-3904.

82A)      W. Adam, M. A. Arnold, M. Gruene, W. M. Nau, U. Pischel, C. R. Saha-Moeller, “Spiroiminodihydantoin Is a Major Product in the Photooxidation of 2′-Deoxyguanosine by the Triplet States and Oxyl Radicals Generated from Hydroxyacetophenone Photolysis and Dioxetane Thermolysis”, Org. Lett. 20024, 537-540.

81R)      W. M. Nau and X. Wang,”Biomolecular and supramolecular kinetics in the submicrosecond time range: the fluorazophore approach”, ChemPhyChem 20023, 393-398.

80A)      U. Pischel, W. M. Nau, “Structure-reactivity relationships in the photoreduction of n,pi*-excited ketones and azoalkanes: The effect of reaction thermodynamics, excited-state electrophilicity, and antibonding character in the transition state”, Photochem. Photobiol. Sci. 20021,141-147.

79A)      R. R. Hudgins, F. Huang, G. Gramlich, W. M. Nau, “A Fluorescence-Based Method for Direct Measurement of Submicrosecond Intramolecular Contact Formation in Biopolymers: An Exploratory Study with Polypeptides”, J. Am. Chem. Soc. 2002124, 556-564.

78A)      X. Zhang, G. Gramlich, X. Wang, W. M. Nau, “A Joint Structural, Kinetic, and Thermodynamic Investigation of Substituent Effects on Host-Guest Complexation of Bicyclic Azoalkanes by b-Cyclodextrin”, J. Am. Chem. Soc. 2002124, 254-263.


77A)      W. Adam, M. A. Arnold, W. M. Nau, U. Pischel, C. R. Saha-Möller, “Structure-Dependent Reactivity of Oxyfunctionalized Acetophenones in the Photooxidation of DNA: Base Oxidation and Strand Breaks through Photolytic Radical Formation (Spin Trapping, EPR Spectroscopy, Transient Kinetics) versus Photosensitization (Electron Transfer, Hydrogen-Atom Abstraction)”, Nucleic Acids Research 200129, 4955-4962.

76C)      C. Marquez, W. M. Nau, “Polarisierbarkeiten im Inneren von molekularen Containern”, Angew. Chem. 2001113, 4515-4518; “Polarizabilities Inside Molecular Containers”, Angew. Chem. Int. Ed. 200140, 4387-4390 (cover page).

75C)      A. Sinicropi, R. Pogni, R. Basosi, M. A. Robb, G. Gramlich, W. M. Nau, M. Olivucci, “Fluoreszenzlöschung über stufenweisen Wasserstoff-, Elektronen- und Protonentransfer in der Umgebung einer konischen Durchdringung”, Angew. Chem. 2001113, 4313-4318; “Fluorescence Quenching via Sequential Hydrogen, Electron, and Proton Transfer in the Proximity of a Conical Intersection”, Angew. Chem. Int. Ed. 200140, 4185-4189.

74A)      U. Pischel, W. M. Nau, “Switch-Over in Photochemical Reaction Mechanism from Hydrogen Abstraction to Exciplex-Induced Quenching: Interaction of Triplet-Excited versus Singlet-Excited Acetone versus Cumyloxyl Radicals with Amines”, J. Am. Chem. Soc. 2001123, 9727-9737.

73A)      X. Wang, W. M. Nau, “Kinetics of One- and Two-Directional Charge Hopping in One-Dimensional Systems. Application to DNA”, ChemPhysChem 20012, 761-766.

72C)      C. Marquez, W. M. Nau, “Zwei Mechanismen für die langsame Wirt-Gast-Komplexierung zwischen Cucurbit[6]uril und Cyclohexylmethylamin: pH-abhängige supramolekulare Kinetik”, Angew. Chem. 2001113, 3248-3254; “Two Mechanisms of Slow Host-Guest Complexation between Cucurbit[6]uril and Cyclohexylmethylamine: pH-Responsive Supramolecular Kinetics”, Angew. Chem. Int. Ed. 200140, 3155-3160.

71A)      B. Mayer, X. Zhang, W. M. Nau, G. Marconi, “Co-conformational Variability of beta-Cyclodextrin Complexes Studied by Induced Circular Dichroism of Azoalkanes”, J. Am. Chem. Soc. 2001123, 5240-5248.

70A)      K. J. Nau-Staudt, W. M. Nau, I.O. Haefliger, J. Flammer, “Lipidperoxidation of Porcine Irises: Dependence on Pigmentation”, Curr. Eye Res. 200122, 229-234.

69A)      K. J. Nau-Staudt, W. M. Nau, I.O. Haefliger, J. Flammer, “Abhängigkeit der Lipidperoxidation von der Pigmentierung porkiner Iris”, Klin. Monatsbl. Augenheilkd. 2001218, 341-344.

68A)      G. Gramlich, J. Zhang, M. Winterhalter, W. M. Nau, “A Long-Lived Amphiphilic Fluorescent Probe Studied in POPC Air-Water Monolayer and Solution Bilayer Systems” Chem. Phys. Lipids 2001113, 1-9.


67R)      W. M. Nau, “n,pi* Photochemistry beyond Ketones”, EPA Newsletter 200070, 6-29.

66C)      A. Sinicropi, U. Pischel, R. Basosi, W. M. Nau, M. Olivucci, “Konische Durchdringungen in ladungstransfer-induzierten Photoreaktionen”, Angew. Chem. 2000112, 4776-4780; “Conical Intersections in Charge-Transfer Induced Quenching”, Angew. Chem. Int. Ed. 200039, 4582-4586.

65T)      W. M. Nau, “Fluorescent Azoalkanes for Exploring Novel Photochemical Applications and Reaction Mechanisms”, Habilitation Thesis, 2000, University of Basel, Switzerland.

64A)      W. Adam, W. Maas, W. M. Nau, “Wavelength-Selective Photodenitrogenation of Azoalkanes to High-Spin Polyradicals with Cyclopentane-1,3-diyl Spin-Carrying Units and Their Photobleaching: EPR/UV Spectroscopy and Product Studies of the Matrix-Isolated Species”, J. Org. Chem. 200065, 8790-8796.

63A)      U. Pischel, X. Allonas, W. M. Nau, “Photoreactions of Azoalkanes with Amines: A Time-Resolved Photoconductivity Study”, J. Inf. Recording 200025, 311-321.

62A)      X. Zhang, C. Erb, J. Flammer, W. M. Nau, “Absolute Rate Constants for the Quenching of Reactive Excited States BY Melanin and Related 5,6-Dihydroxyindole Metabolites: Implications for their Antioxidant Activity”, Photochem. Photobiol. Sci. 200071, 524-533.

61A)      X. Zhang, W. M. Nau, “Fluorazophore-S: An Exceedingly Long-Lived Fluorescent Azoalkane Displaying Enhanced Selectivity towards Antioxidants”, J. Inf. Recording 200025, 323-330.

60A)      U. Pischel, W. M. Nau, “Quenching of n,pi*-Excited Azoalkanes by Amines: Structural and Electronic Effects on Charge Transfer”, J. Phys. Org. Chem. 200013, 640-647.

59C)      X. Zhang, W. M. Nau, “Die Ausrichtung eines Chromophors in einen chiralen Wirtmolekuel liefert einen empfindlichen Test fuer die Orientierungs-Intensitaets-Regel des induzierten Circulardichroismus”, Angew. Chem. 2000112, 555-557; “Chromophore Alignment in a Chiral Host Provides a Sensitive Test for the Orientation-Intensity Rule of Induced Circular Dichroism”, Angew. Chem. Int. Ed. 200039, 544-547.

58A)      X. Zhang, W. M. Nau, “Aryl Substituent Effects and Solvent Effects on the Decarbonylation of Phenacetyl Radicals”, J. Phys. Org. Chem. 200013, 634-639.

57A)      U. Pischel, X. Zhang, B. Hellrung, E. Haselbach, P.-A. Muller, W. M. Nau, “Fluorescence Quenching of n,pi*-Excited Azoalkanes by Amines: What is a Sterically Hindered Amine?”, J. Am. Chem. Soc. 2000122, 2027-2034.

56A)      M. Abe, W. Adam, T. Heidenfelder, W. M. Nau, X. Zhang, “Intramolecular and Intermolecular Reactivity of Localized Singlet Diradicals: The Exceedingly Long-Lived 2,2-Diethoxy-1,3-diphenylcyclopentane-1,3-diyl”, J. Am. Chem. Soc. 2000122, 2019-2026.


55A)      M. Abe, W. Adam, W. M. Nau, M. Nojima, ” Generation of Cyclopentane-1,3-diyl Singlet Biradicals and their Chemical Behavior”, Yuki Hanno Kagaku Toronkai Kenkyu Happyo 199949, 94-97.

54C)      G. Gramlich, W. M. Nau, “A Photoactivable Fluorophore Based on Thiazolidinedione as Caging Group”, Org. Lett. 19991, 603-605.

53A)      F. Kita, W. Adam, P. Jordan, W. M. Nau, J. Wirz, “1,3-Cyclopentanediyl Diradicals: Substituent and Temperature Dependence of Triplet-Singlet Intersystem Crossing”, J. Am. Chem. Soc. 1999121, 9265-9275.

52R)      W. M. Nau, “Fluorescent Probes for Antioxidants and Host-Guest-Complexation: Fluorazophores”, Chimia 199953, 217.

51C)      W. M. Nau, U. Pischel, “Invertierter Lösungsmitteleffekt auf Ladungstransfer im angeregten Zustand”, Angew. Chem. 1999111, 3126-3129; “Inverted Solvent Effect on Charge Transfer in the Excited State”, Angew. Chem. Int. Ed. 199938, 2885-2888.

50A)      W. M. Nau, X. Zhang, “An Exceedingly Long-Lived n,pi*-Fluorescent State as a Distinct Structural and Dynamic Probe for Supramolecular Association: An Exploratory Study of Host Guest Complexation by beta-Cyclodextrins”, J. Am. Chem. Soc. 1999121, 8022-8032.


49A)      M. Abe, W. Adam, W. M. Nau, “Photochemical Generation and Methanol Trapping of Localized 1,3 and 1,4 Singlet Diradicals Derived from a Spiroepoxy-Substituted Cyclopentane-1,3-diyl”, J. Am. Chem. Soc. 1998120, 11304-11310.

48A)      W. M. Nau, “A Fluorescent Probe for Antioxidants”, J. Am. Chem. Soc. 1998120, 12614-12618.

47R)      W. M. Nau, “Biologische Schädigungen durch Radikale und deren Prävention”, in “Risikofaktoren für Augenerkrankungen”, C. Erb, J. Flammer (Hrsg.), Verlag Hans Huber, Bern, 1998, 241-258.

46A)      G. Greiner, M. Feth, H. Rau, W. M. Nau, “The Dual Temperature Dependence of the Fluorescence Lifetimes of 2,3-Diazabicyclo[2.2.2]oct-2-ene (DBO) due to Solvent-Induced Quenching and Deazatization”, J. Inf. Recording 199824, 115-122.

45R)      W. M. Nau, “Pathways for the Photochemical Hydrogen Abstraction by n,pi*-Excited States”, Ber. Bunsenges. Phys. Chem. 1998102, 476-485.

44A)      W. M. Nau, G. Greiner, H. Rau, J. Wall, M. Olivucci, J. C. Scaiano, “The Fluorescence of 2,3-Diazabicyclo[2.2.2]oct-2-ene Revisited: Solvent-Induced Quenching of the n,pi*-Excited State by an Aborted Hydrogen Atom Transfer”, J. Phys. Chem. A 1999103, 1579-1584.

43A)      W. M. Nau, “New Aspects of the Photochemistry of n,pi*-Excited States”, J. Inf. Recording 199824, 105-114.

42A)      W. M. Nau, G. Greiner, H. Rau, M. Olivucci, M. A. Robb, “Discrimination between Hydrogen Atom and Proton Abstraction in the Quenching of n,pi* Singlet-Excited States by Protic Solvents”, Ber. Bunsenges. Phys. Chem. 1998102, 486-492.

41C)      W. M. Nau, G. Greiner, J. Wall, H. Rau, M. Olivucci, M. A. Robb, “Der Mechanismus der Wasserstoffabstraktion durch Moleküle in einem n,pi*-angeregten Singulettzustand: Nachweis für thermische Aktivierung und Desaktivierung über eine konische Durchdringung”, Angew. Chem. 1998110, 103-107; “The Mechanism for Hydrogen Abstraction by n,pi* Singlet-Excited States: Evidence for Thermal Activation and Deactivation through a Conical Intersection”, Angew. Chem. Int. Ed. Engl. 199837, 98-101.

40R)      W. Adam, H. M. Harrer, F. Kita, W. M. Nau, “The EPR Spectroscopic D Parameter of Localized Triplet Diradicals as Probe for Electronic Effects in Benzyl-Type Monoradicals”, Adv. Photochem. 199824, 205-254.

39A)      W. Adam, S. Andler, W. M. Nau, C. R. Saha-Möller, “Oxidative DNA Damage by Radicals Generated in the Thermolysis of Hydroxymethyl-Substituted 1,2-Dioxetanes through the a Cleavage of Chemiexcited Ketones”, J. Am. Chem. Soc. 1998120, 3549 -3559.


38C)      W. M. Nau, “Organic Triradicals and Tetraradicals with Low-Spin and High-Spin States”, Angew. Chem. 1997109, 2551-2554; Angew. Chem. Int. Ed. Engl. 199736, 2445-2448.

37A)      W. M. Nau, W. Adam, D. Klapstein, C. Sahin, H. Walter, “Correlation of Oxidation and Ionization Potentials for Azoalkanes”, J. Org. Chem. 199762, 5128-5132.

36A)      W. Adam, J. N. Moorthy, W. M. Nau, J. C. Scaiano, “Photoreduction of Azoalkanes by Direct Hydrogen Abstraction from 1,4-Cyclohexadiene, Alcohols, Stannanes, and Silanes”, J. Org. Chem. 199762, 8082-8090.

35A)      W. Adam, J. N. Moorthy, W. M. Nau, J. C. Scaiano, “Charge-Transfer-Induced Photoreduction of Azoalkanes by Amines”, J. Am. Chem. Soc. 1997119, 6749-6756.

34A)      W. Adam, J. N. Moorthy, W. M. Nau, J. C. Scaiano, “Solvent Effect on Product Distribution in Photochemical Pathways of alpha C-N versus beta C-C Cleavage of n,pi* Triplet-Excited Azoalkanes”, J. Am. Chem. Soc. 1997119, 5550-5555.

33A)      W. M. Nau, “An Electronegativity Model for Polar Ground State Effects on Bond Dissociation Energies”, J. Phys. Org. Chem. 199710, 445-455.

32R)      W. Adam, C. van Barneveld, O. Emmert, H. M. Harrer, F. Kita, A. S. Kumar, W. Maas, W. M. Nau, S. H. K. Reddy, J. Wirz, “About Monoradicals, Triplet Diradicals and Higher Spin States: Understanding Electronic Substituent Effects through EPR and Time-Resolved UV Spectroscopy”, Pure Appl. Chem. 199769, 735-742.

31A)      W. M. Nau, G. Bucher, J. C. Scaiano, “Absolute Rate Constants for the Reactions of Sulfur (3PJ) Atoms in Solution”, J. Am. Chem. Soc. 1997119, 1961-1970.


30A)      W. M. Nau, “Computational Assessment of Polar Ground State Effects on the Bond Dissociation Energies of Benzylic and Related Bonds”, J. Org. Chem. 199661, 8312-8314.

29C)      W. Adam, J. N. Moorthy, W. M. Nau, J. C. Scaiano, “Photoreduction of Azoalkane Triplet States by Hydrogen Atom and Charge Transfer”, J. Org. Chem. 199661, 8722-8723.

28A)      W. Adam, H. M. Harrer, T. Heidenfelder, T. Kammel, F. Kita, W. M. Nau, C. Sahin, “The D Parameter (Zero-Field Splitting) as a Direct Measure of Structural and Electronic Effects in Localized 1,3-Diradicals”, J. Chem. Soc., Perkin Trans. II 1996, 2085-2089.

27A)      W. Adam, H. M. Harrer, F. Kita, H.-G. Korth, W. M. Nau, “Electronic Effects of para- and meta-Substituents on the EPR D Parameter in 1,3-Arylcyclopentane-1,3-diyl Triplet Diradicals. A New Spectroscopic Measure of alpha Spin Densities and Radical Stabilization Energies in Benzyl-Type Monoradicals”, J. Org. Chem. 199762, 1419-1426.

26A)      W. Adam, F. Kita, H. M. Harrer, W. M. Nau, R. Zipf, “The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in para-Substituted Benzyl-Type Radicals”, J. Org. Chem. 199661, 7056-7065.

25A)      W. M. Nau, J. C. Scaiano, “Oxygen Quenching of Excited Aliphatic Ketones and Diketones”, J. Phys. Chem. 1996100, 11360-11367.

24A)      W. M. Nau, W. Adam, J. C. Scaiano, “Fluorescence Quenching of Azoalkanes by Solvent-Assisted Radiationless Deactivation Involving C-H Bonds”, Chem. Phys. Lett. 1996253, 92-96.

23C)      W. Adam, C. van Barneveld, S. E. Bottle, H. Engert, G. R. Hanson, H. M. Harrer, C. Heim, W. M. Nau, D. Wang, “EPR Characterization of the Quintet State for a Hydrocarbon Tetraradical with Two Localized 1,3-Cyclopentanediyl Biradicals Linked by meta-Phenylene as a Ferromagnetic Coupler”, J. Am. Chem. Soc. 1996118, 3974-3975.

22C)     W. M. Nau, W. Adam, J. C. Scaiano, “Singlet Oxygen Production from Excited Azoalkanes”, J. Am. Chem. Soc. 1996118, 2742-2743.

21A)      W. M. Nau, F. L. Cozens, J. C. Scaiano, “Reactivity and Efficiency of Singlet- and Triplet-Excited States in Intermolecular Hydrogen Abstraction Reactions”, J. Am. Chem. Soc. 1996118, 2275-2282.

20R)      W. Adam, H. M. Harrer, F. Kita, W. M. Nau, “Localized Triplet Diradicals as a Probe for Electronic Substituent Effects in Benzyl-Type Radicals: The DD Scale”, Pure Appl. Chem. 199769, 91-96.


19A)      W. Adam, G. Fragale, D. Klapstein, W. M. Nau, J. Wirz, “Phosphorescence and Transient Absorption of Azoalkane Triplet States”, J. Am. Chem. Soc. 1995117, 12578-12592.

18A)      D. Gernet, W. Kiefer, T. Kammel, W. M. Nau, W. Adam, “Matrix Isolation Raman Spectroscopy and Semiempirical Calculations of 2,3-Diazabicyclo[2.2.1]hept-2-ene (DBH) and Its Photoproduct Bicyclo[2.1.0]pentane (BCP)”, J. Mol. Struct. 1995348, 333-336.

17C)      F. Kita, W. M. Nau, W. Adam, J. Wirz, “Effect of Donor-Acceptor Substitution on Intersystem Crossing Rates of 1,3-Diaryl-1,3-Cyclopentanediyl Triplet Biradicals”, J. Am. Chem. Soc. 1995117, 8670-8671.

16A)      N. L. Campbell, C. J. Gillis, D. Klapstein, W. M. Nau, W. J. Balfour, S. G. Fougère, “Vibrational Spectra and Conformational Behaviour of Carbonyl Isothiocyanates X-CO-NCS, X = F, Cl, Br, MeO, EtO, and Acetyl Isothiocyanate CH3-CO-NCS”, Spectrochim. Acta, Part A 199551A, 787-798.


15A)      W. M. Nau, H. M. Harrer, W. Adam, “Radical Stabilization and Ground State Polar Substituent Effects in the Thermal Decomposition of Azoalkanes”, J. Am. Chem. Soc. 1994116, 10972-10982.

14A)      W. Adam, H. Ammon, W. M. Nau, K. Peters, “4-Halo[4H]pyrazoles: Cycloaddition with Cyclopentadiene to Azoalkanes of the 2,3-Diazabicyclo[2.2.1]hept-2-ene Type versus Electrophilic Addition with Cyclopentene”, J. Org. Chem. 199459, 7067-7071.

13A)      W. J. Balfour, S. G. Fougère, D. Klapstein, W. M. Nau, “The Infrared and Raman Spectra of Carbonyl Diisocyanate”, Spectrochim. Acta, Part A 199450A, 307-316.

12T)      W. M. Nau, “Electronic Substituent Effects on the EPR Zero-Field Splitting Parameters and Lifetimes of Cyclopentanediyl Biradicals as well as on the Thermal Nitrogen Extrusion from Azoalkanes”, Ph.D.-Dissertation, 1994, Julius-Maximilians-University of Würzburg, Würzburg, Germany.

11A)      D. Klapstein, W. M. Nau, “Variable Temperature Infrared Spectroscopy of Chlorocarbonyl Isocyanate Cl-CO-NCO and the Effect of Polarizable Substituents on the Conformations of Carbonyl Isocyanates and Isothiocyanates”, J. Mol. Struct. 1994317, 59-67.

10A)      W. Adam, W. M. Nau, J. Sendelbach, “Temperature Dependence of the alpha versus beta Bond Cleavage in the Direct and Triplet-Sensitized Photolysis of Azoalkanes of the 2,3-Diazabicyclo-[2.2.1]hept-2-ene Type”, J. Am. Chem. Soc. 1994116, 7049-7054.

9A)        D. Klapstein, W. M. Nau, “Spectroscopy of Acyl and Carbonyl Isocyanates”, Spectrochim. Acta, Part A 199450A, 307-316.

8A)        W. Adam, H. M. Harrer, W. M. Nau, K. Peters, “Electronic Substituent Effects on the Acid-Catalyzed [4+2] Cycloaddition of Isopyrazoles with Cyclopentadiene and the Photochemical and Thermal Denitrogenation of the Resulting 1,4-Diaryl-7,7-dimethyl-2,3-diazabicyclo-[2.2.1]hept-2-ene Azoalkanes to Bicyclo[2.1.0]pentanes”, J. Org. Chem. 199459, 3786-3797.


7A)        W. J. Balfour, S. G. Fougère, D. Klapstein, W. M. Nau, “The Infrared and Raman Spectra of Methoxycarbonyl and Thiomethoxycarbonyl Isocyanates”, Can. J. Chem. 199371, 1627-1631.

6C)        W. Adam, W. M. Nau, J. Sendelbach, J. Wirz, “Identification of a Remarkably Long-Lived Azoalkane Triplet State”, J. Am. Chem. Soc. 1993115, 12571-12572.

5A)        D. Klapstein, W. M. Nau, “Conformational Properties of Carbonyl Isocyanates – Stereoelectronic Effects Favouring the Cisoid Conformation”, J. Mol. Struct. 1993299, 29-41.

4C)        W. Adam, L. Fröhlich, W. M. Nau, J. Wirz, “Effects of Symmetrical Diaryl Substitution on Intersystem Crossing in 1,3-Cyclopentanediyl Triplet Biradicals”, J. Am. Chem. Soc. 1993115, 9824-9825.

3A)        W. J. Balfour, S. G. Fougère, D. Klapstein, W. M. Nau, “Vibrational Spectra of Acetyl Isocyanate and Mono-, Di- and Trichloroacetyl Isocyanates”, J. Mol. Struct. 1993299, 21-28.1383-1384;

2C)        W. Adam, L. Fröhlich, W. M. Nau, H.-G. Korth, R. Sustmann, “Substituenteneinflüsse auf die Nullfeldparameter von lokalisierten Triplett-1,3-Cyclopentandiyl-Diradikalen”, Angew. Chem. 1993105, “Substituent Effects on the Zero-Field Splitting Parameters of Localized Triplet 1,3-Cyclopentanediyl Biradicals”, Angew. Chem. Int. Ed. Engl. 199332, 1339-1340.


1T)        W. M. Nau, “A Spectroscopic Study of Acyl Isocyanates and Acyl Isothiocyanates”, M. Sc. Thesis, 1991, St. Francis Xavier University, Antigonish, Nova Scotia, Canada.


11.87 – 08.90       Study of Chemistry (Diploma) at the University of Würzburg, Germany

09.90 – 12.91       Graduate Studies in Chemistry at St. Francis Xavier University, Canada

       04.12.91       Defense of M.Sc. Thesis (supervisor: Prof. Dr. Dieter Klapstein):

                            "Spectroscopic Studies of Acyl Isocyanates and Acyl Isothiocyanates"

       03.05.92       Graduation as Master of Science in Chemistry, M.Sc.

01.92 – 07.94       Ph.D. studies in Chemistry at the University of Würzburg, Germany

       20.06.94       Submission of Ph.D. thesis (supervisor: Prof. Dr. Waldemar Adam):

                            "Electronic Substituent Effects on the ESR Zero-Field Parameters and
                            Lifetimes of Triplet Cyclopentanediyl Diradicals and …"

       16.08.94       Degree: "Ph.D. in science", Dr. rer. nat.

09.94 – 12.95       Postdoctoral research with Prof. Dr. J. C. "Tito" Scaiano at the University of
                            Ottawa, Canada

01.96 – 03.97       Research Associate at the University of Basel, Switzerland

04.97 – 02.00       Lecture Assistant and Research Director at the University of Basel, Switzerland

03.00 –06.02       Assistant Professor at the University of Basel

07.02 – 02.04      Adjunct Professor of Chemistry at the University of Basel

since 07.02          (Full) Professor of Chemistry at Jacobs University Bremen

03.12–05.14        Elected Dean for Natural Sciences

06.14 –05.23       Dean for the Focus Area Health and Undergraduate Education

since 05.23         Appointed Interim Provost, Vice-President, and Head of Academic Operations

06.90 – 12.91      Fellowship of the Studienstiftung des Deutschen Volkes

       20.07.90       Faculty Prize 1989 at the University of Würzburg (for best Diploma)

07.92 – 06.94       Kekulé Fellowship of the Fonds der Chemischen Industrie

       26.08.94       Study-Achievement-Stipend of the Fonds der Chemischen Industrie

09.94 – 08.95       NATO Fellowship (DAAD)

09.94 – 12.95       Canada International Fellowship (NSERC, Canada)

       21.07.95       Faculty Prize 1994 at the University of Würzburg (for best Ph.D. Thesis)

06.96 – 10.98       Liebig Fellowship of the Fonds der Chemischen Industrie

07.98 – 09.01       Profil-Fellowship of the Swiss National Science Foundation

       26.02.00       International Grammaticakis–Neumann Prize of the European Photochemistry Association

03.00 – 02.04       SNF Professorship of the Swiss National Science Foundation

       19.03.01        ADUC-Jahrespreis für Habilitanden 2000

       17.10.02        Werner Prize 2002 of the Swiss Chemical Society

       16.7.2010      EPA-PPS Prize 2010

            04.13       INNOLEC Lectureship, Masaryk University, Brno, Czech Republic

            08.16       Admitted as Fellow of the Royal Chemical Society

            08.17       Distinguished Professorship, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China

            06.18       Appointment as High-End Foreign Expert by State Administration of Foreign Experts Affairs, China

07.98 – 10.98       W. F. James Chair Professor of Pure and Applied Sciences at St. Francis Xavier University in Antigonish, Nova Scotia, Canada

08.01 – 12.01       Margaret L. and Harlan L. Goering Professor in Organic Chemistry at the University of Wisconsin in Madison, USA

03.02 – 06.02       Visiting Professor of Chemistry at the International University Bremen

             12.09       Visiting Professor at the University of Huelva, Spain

01.10 – 06.10       Leverhulme Visiting Professor of Chemistry and Physics at the University of Cambridge, UK

07.10 – 08.10      Visiting Professor at the Institute of Chemical Research of Catalonia (ICIQ) in Tarragona, Spain

10.15 – 10.18       Guest Professor at the China University of Petroleum (East China) in Qingdao, China

08.21 – 08.23      Honorary Faculty Member at Indian Institute of Technology IIT Guwahati, India

01.22 – 08.23      Appointment as Concurrent Professor of Hubei Province at Wuhan Textile Industry, China.

  • Member of the Society of German Chemists (GDCh)
  • Vice Chairman (re-elected for 2010-2013), Executive Member (elected for 2005-2009, re-elected for 2010-2013), and Member of the Photochemistry Section of the GDCh
  • Member of the Liebig-Society for Organic Chemistry
  • Member of the American Chemical Society (ACS) and Organic Chemistry Division
  • Member of the Royal Chemical Society
  • Past President (elected 2014-2016), President (elected 2012-2014), Vice President (elected for 2010-2012), European Executive Committee Member (elected for 2007-2010, re-elected for 2011-2012), National Representative (2001-2004 for Switzerland, 2007-2008 for Germany), and Member of the European Photochemistry Association (EPA)
  • Member and Executive Member (until 2004) of the Swiss Society of Photochemistry and Photophysics (SGPP), now Section Photochemistry of the SCG
  • Executive Board Member of the International Foundation of Photochemistry (since 2014)
Data Analysis

Here we provide many of the fitting functions developed in the Nau group as well as a JavaScript-based tool to calculate the degree of complexation. The functions are available for Origin (for PCs) and ProFit (for Mac) and can be used with binding titration data obtained from absorption, fluorescence, circular dichroism and NMR in the fast exchange limit.

Fitting Functions

The files come as password-protected zip-files including exemplary data for validation.